Ruthenium-Catalyzed C-H Bond Arylations of Arenes Bearing Removable Directing Groups via Six-Membered Ruthenacycles

被引：155

作者：

Ackermann, Lutz ^{[1
]}

Diers, Emelyne ^{[1
]}

Manvar, Atul ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

ORGANIC LETTERS | 2012年 / 14卷 / 04期

关键词：

PHOSPHINE OXIDES; ARYL; FUNCTIONALIZATION; ACTIVATION; PRELIGANDS; PALLADIUM; PHENOLS; BROMIDES; SYSTEM;

D O I：

10.1021/ol3000876

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ruthenium-catalyzed direct arylations of phenols bearing removable directing groups were accomplished through carboxylate assistance via six-membered ruthenacycles as key intermediates.

引用

页码：1154 / 1157

页数：4

共 60 条

[11] Ruthenium-Catalyzed Oxidative Annulation by Cleavage of C-H/N-H Bonds [J].

Ackermann, Lutz ;

Lygin, Alexander V. ;

Hofmann, Nora .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (28) :6379-6382

[12] Ruthenium-Catalyzed Direct C-H Bond Arylations of Heteroarenes [J].

Ackermann, Lutz ;

Lygin, Alexander V. .

ORGANIC LETTERS, 2011, 13 (13) :3332-3335

[13] Carboxylate-Assisted Transition-Metal-Catalyzed C-H Bond Functionalizations: Mechanism and Scope [J].

Ackermann, Lutz .

CHEMICAL REVIEWS, 2011, 111 (03) :1315-1345

[14] Carboxylate-Assisted Ruthenium-Catalyzed Direct Alkylations of Ketimines [J].

Ackermann, Lutz ;

Hofmann, Nora ;

Vicente, Ruben .

ORGANIC LETTERS, 2011, 13 (07) :1875-1877

[15] Air-Stable Bifunctional HASPO Preligands for Metal-Catalyzed Cross-Couplings and Direct C-H Bond Arylations [J].

Ackermann, Lutz .

ISRAEL JOURNAL OF CHEMISTRY, 2010, 50 (5-6) :652-663

[16] Mechanistic Insight into Direct Arylations with Ruthenium(II) Carboxylate Catalysts [J].

Ackermann, Lutz ;

Vicente, Ruben ;

Potukuchi, Harish K. ;

Pirovano, Valentina .

ORGANIC LETTERS, 2010, 12 (21) :5032-5035

[17] Regioselective syntheses of fully-substituted 1,2,3-triazoles: the CuAAC/C-H bond functionalization nexus [J].

Ackermann, Lutz ;

Potukuchi, Harish Kumar .

ORGANIC & BIOMOLECULAR CHEMISTRY, 2010, 8 (20) :4503-4513

[18] Ruthenium-Catalyzed C-H Bond Functionalizations of 1,2,3-Triazol-4-yl-Substituted Arenes: Dehydrogenative Couplings Versus Direct Arylations [J].

Ackermann, Lutz ;

Novak, Petr ;

Vicente, Ruben ;

Pirovano, Valentina ;

Potukuchi, Harish K. .

SYNTHESIS-STUTTGART, 2010, (13) :2245-2253

[19] Transition-metal-catalyzed direct arylations via C-H bond cleavages [J].

Ackermann, Lutz .

PURE AND APPLIED CHEMISTRY, 2010, 82 (07) :1403-1413

[20] Ruthenium-Catalyzed Direct Arylations Through C-H Bond Cleavages [J].

Ackermann, Lutz ;

Vicente, Ruben .

C-H ACTIVATION, 2010, 292 :211-229

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