Vysis® UroVysion for the detection of urothelial carcinoma

被引:74
作者
Halling, KC [1 ]
机构
[1] Mayo Clin & Mayo Fdn, Dept Lab Med & Pathol, Div Lab Genet, Rochester, MN 55905 USA
基金
美国国家科学基金会;
关键词
bladder cancer; bladder tumor markers; FISH; urine cytology; urothelial carcinoma; Vysis (R) UroVysion;
D O I
10.1586/14737159.3.4.507
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
For decades, cystoscopy and urine cytology have been the mainstay for monitoring superficial urothelial carcinoma patients for tumor recurrence. However, urine cytology has poor sensitivity for urothelial carcinoma and, consequently, numerous investigators have been endeavoring to develop more sensitive assays for the detection of urothelial carcinoma. This article presents an overview of the types of new assays that have been developed for urothelial carcinoma detection but focuses primarily on the features and performance of a new fluorescence in situ hybridization assay for urothelial carcinoma detection known as Vysis(R) UroVysion.
引用
收藏
页码:507 / 519
页数:13
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