In vitro activity of certain antimicrobial agents in combination with Augouardia letestii hexane extracts against methicillin-resistant Staphylococcus aureus

被引：0
|
作者：
Obiang-Obounou, Brice W. [1 ,2 ]
Choi, Jang-Gi [1 ,2 ]
Lee, Young-Seob [1 ,2 ]
Kang, Ok-Hwa [1 ,2 ,4 ]
Oh, You-Chang [1 ,2 ]
Keum, Joon-Ho [1 ,2 ]
Maroufath, Lamidi [3 ]
Rho, Jung-Rae [4 ]
Shin, Dong-Won [5 ]
Kwon, Dong-Yeul [1 ,2 ]
机构：
[1] Wonkwang Univ, Coll Pharm, Jeonbuk 570749, South Korea
[2] Wonkwang Univ, Wonkwang Oriental Med Res Inst, Jeonbuk 570749, South Korea
[3] Natl Ctr Res & Technol CENAREST, Inst Tradit Pharmacopoeia & Med IPHAMETRA, Libreville, Gabon
[4] Kunsan Natl Univ, Dept Oceanog, Kunsan 573701, South Korea
[5] Sunchon Natl Univ, Dept Oriental Med Resources, Jeonnam 540742, South Korea
来源：
AFRICAN JOURNAL OF BIOTECHNOLOGY | 2011年 / 10卷 / 65期
关键词：
Augouardia lestestii; antimicrobial activity; synergistic combinations; drug-resistance; NATURAL-PRODUCTS; SYNERGY; ANTIBIOTICS;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The ability of methicillin-resistant Staphycoccus aureus to acquire resistance to most antibiotics is a worldwide concern that necessitated the study of the antimicrobial activity of the medicinal plant Augouardia lestestii alone and in combination with existing antibiotics. The minimum inhibitory concentration was determined by broth microdilution method and the evaluation of synergy was determined by the checkerboard dilution test. In this study, the antimicrobial activity of A. lestestii leaves, stem barks and roots were investigated against methicillin resistant S. aureus strains. The A. lestestii hexane fraction showed good antibacterial activity against all strains with minimum inhibitory concentration ranging from 125 to 250 mu g/ml. Further, synergistic effects were observed for all antibiotics (ampicillin, norfloxacin, ciprofloxacin and erythromycin) except for nisin. The study also validated the traditional use of A. lestestii against infectious diseases.
引用
收藏
页码：14644 / 14648
页数：5
相关论文
共 50 条
  • [11] Efficacy of combination oral antimicrobial agents against biofilm-embedded methicillin-resistant Staphylococcus aureus
    Wu, Wen-Shiann
    Chen, Chi-Chung
    Chuang, Yin-Ching
    Su, Bo-An
    Chiu, Yu-Hsin
    Hsu, Hui-Jine
    Ko, Wen-Chien
    Tang, Hung-Jen
    JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION, 2013, 46 (02) : 89 - 95
  • [12] In Vitro Antimicrobial Activity of Aminoreductone against the Pathogenic Bacteria Methicillin-Resistant Staphylococcus aureus (MRSA)
    Vu Thu Trang
    Takeuchi, Hiroaki
    Kudo, Hayato
    Katsuno, Shinya
    Shimamura, Tomoko
    Kashiwagi, Takehiro
    Vu Hong Son
    Sugiura, Tetsuro
    Ukeda, Hiroyuki
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2011, 59 (16) : 8953 - 8960
  • [13] In vitro activity of diastereomeric antimicrobial peptides alone and in combination with antibiotics against methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa
    Innate Immunity Research Unit, National Institute of Agrobiological Science, Tsukuba, Ibaraki 305-8634, Japan
    不详
    J. Insect Biotechnol. Sericology, 2007, 1 (25-29):
  • [14] Antimicrobial activity of hydralazine against methicillin-resistant and methicillin-susceptible Staphylococcus aureus
    Stefany Aires do Nascimento, Francisca B.
    do Amaral Valente Sa, Livia Gurgel
    de Andrade Neto, Joao B.
    da Silva, Lisandra Juvencio
    Rodrigues, Daniel Sampaio
    de Farias Cabral, Vitoria P.
    Barbosa, Amanda Dias
    Almeida Moreira, Lara E.
    Braga Vasconcelos, Camille R.
    Cavalcanti, Bruno Coelho
    Franca Rios, Maria E.
    Silva, Jacilene
    Marinho, Emmanuel Silva
    dos Santos, Helcio Silva
    de Mesquita, Jaco R. L.
    Pinto Lobo, Marina Duarte
    de Moraes, Manoel Odorico
    Nobre Junior, Helio, V
    da Silva, Cecilia Rocha
    FUTURE MICROBIOLOGY, 2024, 19 (02) : 91 - 106
  • [15] In vitro activity of fosfomycin in combination with linezolid against clinical isolates of methicillin-resistant Staphylococcus aureus
    Yu Xu-hong
    Falagas, Matthew E.
    Dong, Wang
    Karageorgopoulos, Drosos E.
    Lin De-feng
    Rui, Wang
    JOURNAL OF ANTIBIOTICS, 2014, 67 (05): : 369 - 371
  • [16] In vitro activity of fosfomycin in combination with linezolid against clinical isolates of methicillin-resistant Staphylococcus aureus
    Yu Xu-hong
    Matthew E Falagas
    Wang Dong
    Drosos E Karageorgopoulos
    Lin De-feng
    Wang Rui
    The Journal of Antibiotics, 2014, 67 : 369 - 371
  • [17] In vitro activity of ceftaroline against methicillin-resistant Staphylococcus aureus isolates
    Basireddy, S.
    Singh, M.
    Ali, S.
    Kabra, V.
    INDIAN JOURNAL OF MEDICAL MICROBIOLOGY, 2015, 33 (03) : 464 - +
  • [18] Comparative in vitro activity of oritavancin and other agents against methicillin-susceptible and methicillin-resistant Staphylococcus aureus
    Sweeney, Debora
    Shinabarger, Dean L.
    Arhin, Francis F.
    Belley, Adam
    Moeck, Greg
    Pillar, Chris M.
    DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2017, 87 (02) : 121 - 128
  • [19] Antimicrobial Resistance in Methicillin-Resistant Staphylococcus aureus to Newer Antimicrobial Agents
    Watkins, Richard R.
    Holubar, Marisa
    David, Michael Z.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2019, 63 (12)
  • [20] Plant Flavonoids with Antimicrobial Activity against Methicillin-Resistant Staphylococcus aureus (MRSA)
    Xu, Shengnan
    Kang, Ayue
    Tian, Yue
    Li, Xinhui
    Qin, Shangshang
    Yang, Ruige
    Guo, Yong
    ACS INFECTIOUS DISEASES, 2024, 10 (09): : 3086 - 3097
12345