Subclinical electrophysiological alterations of phrenic nerve in chronic inflammatory demyelinating polyneuropathy

被引：2

作者：

Cocito, D

Ciaramitaro, P

Rota, E

Isoardo, G

Cannizzo, S

Poglio, F

Tavella, A

Castelli, L

Paolasso, I

Bergamasco, B

Baldi, S

机构：

[1] Univ Turin, Dipartimento Neurosci, UO Neurofisiol Clin, I-10126 Turin, Italy

[2] IRCCS, Fdn S Maugeri, Pavia, Italy

[3] Osped CTO, Div Neurochirurg, Neurofisiol Clin, Turin, Italy

[4] Osped Civile, SOC Neurol, Asti, Italy

[5] ASO San Giovanni Battista, SOC Pneumol, Turin, Italy

来源：

JOURNAL OF NEUROLOGY | 2005年 / 252卷 / 08期

关键词：

phrenic nerve conduction; chronic inflammatory demyelinating polyneuropathy; CIDP; pulmonary function; electrodiagnosis;

D O I：

10.1007/s00415-005-0780-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Alterations of the phrenic nerve (PN) and pulmonary function tests (PFTs) have been described in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). This study was aimed at assessing the relationship between PN and respiratory function in CIDP patients without clinical signs of respiratory failure. Bilateral PN and right median nerve conduction studies were carried out along with blood gas analysis and PFTs: maximal inspiratory pressure; maximal expiratory pressure; forced vital capacity. The amplitude of the compound muscle action potential of the PN was seen to be altered in 19/24 (79%) patients and latency in 22 (92%). Eighteen patients (75%) showed at least one abnormal PFTs or CO2 partial pressure value. Electrophysiological alterations of the PN were observed in a high percentage of the CIDP patients studied. No statistically significant correlation was observed between PN and PFTs alterations.

引用

页码：916 / 920

页数：5