Increment Antimicrobial Resistance During the COVID-19 Pandemic: Results from the Invifar Network

被引：47

作者：

Lopez-Jacome, Luis Esau ^{[1
]}

Fernandez-Rodriguez, Diana ^{[1
]}

Franco-Cendejas, Rafael ^{[1
]}

Camacho-Ortiz, Adrian ^{[2
]}

Morfin-Otero, Maria del Rayo ^{[3
]}

Rodriguez-Noriega, Eduardo ^{[4
]}

Ponce-de-Leon, Alfredo ^{[4
]}

Ortiz-Brizuela, Edgar ^{[4
]}

Rojas-Larios, Fabian ^{[5
]}

Velazquez-Acosta, Maria del Consuelo ^{[6
]}

Mena-Ramirez, Juan Pablo ^{[7
,8
]}

Rodriguez-Zulueta, Patricia ^{[9
]}

Bolado-Martinez, Enrique ^{[10
]}

Quintanilla-Cazares, Luis Javier ^{[11
]}

Aviles-Benitez, Laura Karina ^{[12
]}

Consuelo-Munoz, Scarlett ^{[13
]}

Choy-Chang, Elena Victoria ^{[14
]}

Feliciano-Guzman, Jose Manuel ^{[15
]}

Couoh-May, Carlos Antonio ^{[16
]}

Lopez-Gutierrez, Eduardo ^{[17
]}

Molina-Jaimes, Aaron ^{[18
]}

Rincon-Zuno, Joaquin ^{[19
]}

Gil-Veloz, Mariana ^{[20
]}

Alcaraz-Espejel, Margarita ^{[21
]}

Corte-Rojas, Reyna Edith ^{[22
]}

Gomez-Espinosa, Josue ^{[23
]}

Monroy-Colin, Victor Antonio ^{[24
]}

Morales-de-la-Pena, Cecilia Teresita ^{[25
]}

Aguirre-Burciaga, Efren ^{[26
]}

Lopez-Moreno, Laura Isabel ^{[27
]}

Martinez-Villarreal, Rebeca Thelma ^{[28
]}

Cetina-Umana, Carlos Miguel ^{[29
]}

Galindo-Mendez, Mario ^{[30
]}

Soto-Nieto, Gabriel Israel ^{[31
]}

Cobos-Canul, Dulce Isabel ^{[32
]}

Moreno-Mendez, Martha Irene ^{[33
]}

Tello-Gomez, Esmeralda ^{[34
]}

Romero-Romero, Daniel ^{[35
]}

Quintana-Ponce, Sandra ^{[36
]}

Peralta-Catalan, Raul ^{[37
]}

Valadez-Quiroz, Alejandro ^{[38
]}

Molina-Chavarria, Alejandro ^{[39
]}

Padilla-Ibarra, Cecilia ^{[40
]}

Barroso-Herrera-y-Cairo, Irma Elena ^{[41
]}

Duarte-Miranda, Lizbeth Soraya ^{[42
]}

Lopez-Lopez, Dulce Maria ^{[43
]}

Escalante-Armenta, Samuel Pavel ^{[44
]}

Osorio-Guzman, Monica Jazmin ^{[45
]}

Lopez-Garcia, Maribel ^{[46
]}

Garza-Ramos, Ulises ^{[47
]}

机构：

[1] Inst Nacl Rehabil Lis Guillermo Ibarra Ibara, Div Infectol, Mexico City, DF, Mexico

[2] Univ Autonoma Nuevo Leon, Infectol, Fac Med, Hosp Univ Dr Jose Eleuterio Gonzalez, Monterrey, Mexico

[3] Univ Guadalajara, Hosp Civil Guadalajara Fray Antonio Alcalde, Infectol, Guadalajara, Mexico

[4] Inst Nacl Ciencias Med Nutr Salvador Zubiran, Infectol, Mexico City, DF, Mexico

[5] Univ Colima, Fac Med, Lab Ecol Microbiol, Colima, Mexico

[6] Inst Nacl Cancerol, Lab Microbiol, Mexico City, DF, Mexico

[7] Univ Guadalajara, Lab, Hosp Gen Zona 21 IMSS, Tepatitlan Morelos, Mexico

[8] Univ Guadalajara, Ctr Univ Altos CUALTOS, Tepatitlan Morelos, Mexico

[9] Hosp Gen Dr Manuel Gea Gonzalez, Infectol, Mexico City, DF, Mexico

[10] Univ Sonora, Dept Ciencias Quim Biol, Hermosillo, Mexico

[11] Hosp Angeles Valle Oriente, Lab, San Pedro Garza Garcia, Mexico

[12] Hosp Infantil Morelia Eva Samano Lopez Mateos, Lab Microbiol Parasitol, Morelia, Michoacan, Mexico

[13] SwissHosp, Bacteriol, Monterrey, Mexico

[14] Hosp Gen Zona 1 IMSS Nueva Frontera, Lab Analisis Clin, Dept Bacteriol, Tapachula, Mexico

[15] Hosp Especialidades Pediat, Lab Patol Clin, Tuxtla Gutierrez, Mexico

[16] Hosp Gen Dr Agustin O Horan, Lab Clin, Merida, Mexico

[17] Hosp Reg Alta Espcial Oaxaca, Lab Microbiol, San Bartolo Coyotepec, Mexico

[18] Hosp Reg Alta Espcial Bicentenario Independencia, Infectol Unidad Vigilancia Epidmiol Hosp, Tultitlan Mariano Escobe, Mexico

[19] Hosp Nino, Infectol, Toluca, Mexico

[20] Hosp Reg Alta Espcial Bajio, Serv Clin, Leon, Mexico

[21] Dept Microbiol Sanatorio Luz, Morelia, Mexico

[22] Hosp Nino Poblano, Lab Clin, Puebla, Mexico

[23] Hosp Dr Jesus Gilberto Gomez Maza, Bacteriol, Tuxtla Gutierrez, Mexico

[24] Ctr Hosp Miguel Hidalgo, Dept Pediat, Aguascalientes, Aguascalientes, Mexico

[25] Hosp Gen Con Especialidades Juan Maria Salvatierr, Lab Clin, La Paz, Mexico

[26] Hosp Reg Delicias, Lab, Ciudad Delicias, Mexico

[27] Hosp Galenia, Lab Clin, Cancun, Mexico

[28] Ctr Univ Salud UANL, Lab Clin, Guadalupe, Mexico

[29] Hosp Materno Infantil Morelos, Lab Clin, Chetmal, Quintana Roo, Mexico

[30] Lab Galindo SC, Direcc Gen, Oaxaca, Oaxaca, Mexico

[31] Inst Nacl Cardiol Ignacio Chavez, Infectol, Mexico City, DF, Mexico

[32] Hosp Gen Chetumal, Lab Analisis Clin, Chetmal, Mexico

[33] Lab Ctr, Bacteriol, Zamora, Mexico

[34] Hosp Gen Dr Miguel Silva, Lab, Morelia, Mexico

[35] Analisis Bioquimico Clin Louis Pasteur, Microbiol, Toluca, Mexico

[36] Univ Autonoma Guerrero, Lab Clin, Escuela Super Ciencias Nat, Chilpancingo, Guerrero, Mexico

[37] Hosp Gen Dr Raymundo Abarca Alarcon, Lab Clin, Chilpancingo Bravo, Mexico

[38] Hosp Especialidades Materno Infantil Leon, Lab, Leon, Mexico

[39] ISSSTESON, Ctr Med Dr Ignacio Chavez, Lab, Hermosillo, Mexico

[40] Hosp Gen Estado Dr Ernesto Ramos Bours, Lab Clin, Hermosillo, Mexico

[41] Hosp Dr Fernando Ocarranza, Lab Clin, Hermosillo, Mexico

[42] ISSSTESON, Ctr Integral Atenc Salud, Lab, Hermosillo, Mexico

[43] Hosp L Adolfo Lopez Mateos, Lab, Obregon, Mexico

[44] Hosp Gen Ciudad Obregon, Bacteriol Med, Obregon, Mexico

[45] Hosp Gen Leon, Infectol, Leon, Mexico

[46] Hosp Madre Nino Guerrerense, Lab Analisis Clin, Chilpancingo Bravo, Mexico

[47] Instituto Nacl Salud Publ, Lab Resistencia Bacteriana, Cuernavaca, Mexico

[48] Univ Autonoma Nuevo Leon, Hosp Univ Dr Jose Eleuterio Gonzalez, Fac Med, BioQuim Med Mol, Monterrey, Mexico

来源：

MICROBIAL DRUG RESISTANCE | 2022年 / 28卷 / 03期

关键词：

antimicrobial resistance; COVID-19; pandemic; INVIFAR; Staphylococcus aureus; Enterococcus faecium; Acinetobacter baumannii complex; Pseudomonas aeruginosa; Klebsiella pneumoniae; Enterobacter cloacae; Escherichia coli;

D O I：

10.1089/mdr.2021.0231

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Aim: This study aims to assess the changes in antimicrobial resistance among some critical and high-priority microorganisms collected previously and during the coronavirus disease 2019 (COVID-19) pandemic in Mexico.Methods: We collected antimicrobial susceptibility data for critical and high-priority microorganisms from blood, urine, respiratory samples, and from all specimens, in which the pathogen may be considered a causative agent. Data were stratified and compared for two periods: 2019 versus 2020 and second semester 2019 (prepandemic) versus the second semester 2020 (pandemic).Results: In the analysis of second semester 2019 versus the second semester 2020, in blood samples, increased resistance to oxacillin (15.2% vs. 36.9%), erythromycin (25.7% vs. 42.8%), and clindamycin (24.8% vs. 43.3%) (p <= 0.01) was detected for Staphylococcus aureus, to imipenem (13% vs. 23.4%) and meropenem (11.2% vs. 21.4) (p <= 0.01), for Klebsiella pneumoniae.In all specimens, increased ampicillin and tetracycline resistance was detected for Enterococcus faecium (p <= 0.01). In cefepime, meropenem, levofloxacin, and gentamicin (p <= 0.01), resistance was detected for Escherichia coli; and in piperacillin-tazobactam, cefepime, imipenem, meropenem, ciprofloxacin, levofloxacin, and gentamicin (p <= 0.01), resistance was detected for Pseudomonas aeruginosa.Conclusion: Antimicrobial resistance increased in Mexico during the COVID-19 pandemic. The increase in oxacillin resistance for S. aureus and carbapenem resistance for K. pneumoniae recovered from blood specimens deserves special attention. In addition, an increase in erythromycin resistance in S. aureus was detected, which may be associated with high azithromycin use. In general, for Acinetobacter baumannii and P. aeruginosa, increasing resistance rates were detected.

引用

页码：338 / 345

页数：8

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