Chemotaxonomic significance of lindenane sesquiterpenoid dimers and eudesmane sesquiterpenoids from Chloranthus henryi Hemsl. var. hupehensis (Pamp.) K. F. Wu

被引:9
作者
Zhang, Dan-Yang [1 ]
Wang, Xiao-Xia [1 ]
Wang, Min [2 ,3 ]
Su, Bai-Lin [1 ]
Wang, Ya-Xin [1 ]
Li, Jin-Yu [1 ]
Yi, Jing [1 ]
Zhuang, Peng-Yu [1 ]
Liu, Hang [2 ,3 ]
机构
[1] North China Univ Sci & Technol, Sch Pharm, Tangshan 063210, Peoples R China
[2] Nanjing Univ, Dept Pharm, Affiliated Drum Tower Hosp, Sch Med, Nanjing 210008, Jiangsu, Peoples R China
[3] Nanjing Med Ctr Clin Pharm, Nanjing 210008, Jiangsu, Peoples R China
关键词
Sesquiterpenoid dimers; Eudesmane sesquiterpenoids; Chloranthus; Chemotaxonomic; CONSTITUENTS; TERPENOIDS; PLANTS;
D O I
10.1016/j.bse.2021.104330
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Seventeen known compounds were isolated from the 95% alcohol extract of the aerial parts of Chloranthus henryi Hemsl. var. hupehensis (Pamp.) K. F. Wu, including five lindenane sesquiterpenoid dimers (1-5) and twelve eudesmane sesquiterpenoids (6-17). In the present research, compounds 3 sarcaglabrin C, 6 neolitacumone C, 7 ent-Atractylenolide III and 8 dehydrocarissone were reported from the Chloranthus genus for the first time, and compounds 1 spicachlorantin B, 2 chloramultilide C, 4 shizukaol B, 5 japonicone C, 9 6 alpha-hydroxyeudesma-4 (15),7(11),8(9)-triene-12,8-olide, 10 ent-(3R)-3-hydroxyatractylenolide III, 11 8 beta H-hydroxyeudesma-4(14),7 (11)-dien-12,8-olide, 12 lasianthuslactone A, 13 (5S,6R,8S,10R)-6-hydroxyeudesma-4(15),7(11)-diene-12,8-olide, 14 4 beta-hydroxy5 alpha,8 beta(H)-eudesm-7(11)-en-8,12-olide, 15 4 beta,8 beta-dihydroxy-5 alpha(H)-eudesm-7(11)-en-8,12olide, 16 curcolonol and 17 1 beta, 8 beta-dihydroxyeudesm -3,7(11)-dien-8 alpha,12-olide were firstly isolated from the plant. Their structures were elucidated on the basis of extensive spectroscopic and chemical analyses. Moreover, the chemotaxonomic significance of the isolated compounds is discussed.
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页数:4
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