Electrophoretic Transport of Biomolecules through Carbon Nanotube Membranes

被引：31

作者：

Sun, Xinghua ^{[1
]}

Su, Xin ^{[1
]}

Wu, Ji ^{[1
]}

Hinds, Bruce J. ^{[1
]}

机构：

[1] Univ Kentucky, Dept Chem & Mat Engn, Lexington, KY 40506 USA

来源：

LANGMUIR | 2011年 / 27卷 / 06期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

NANOPOROUS MEMBRANES; PROTEIN-TRANSPORT; MASS-TRANSPORT; NET CHARGE; SEPARATION; LYSOZYME; MOLECULES; FLOW; DIFFUSION; MOBILITY;

D O I：

10.1021/la104242p

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Electrophoretic transport of proteins cross electrochemically oxidized multi-walled carbon nanotube (MWCNT) membranes has been investigated. A small charged protein, lysozyme, was successfully pumped MWCNT membranes by an electric field while rejecting larger of lysozome was reduced by a factor of about 30 in comparison to bulk mobility and consistent with the production for hindered transport. Mobilities between 0.33 and 1.4 x 10(-9) m(2) V-1 s(-1) were observed and are approximately 10-fold faster than comparable ordered nanoporous membranes and consistent with continuum models. For mixtures of BSA and lysozyme, complete rejection of BSA is seen with electrophoretic separations.

引用

页码：3150 / 3156

页数：7

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