Simple Strategies for Vaginal Health Promotion in Cancer Survivors

被引:88
作者
Carter, Jeanne [1 ,2 ]
Goldfrank, Deborah [2 ]
Schover, Leslie R. [3 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Dept Psychiat & Behav Sci, New York, NY 10065 USA
[2] Mem Sloan Kettering Canc Ctr, Dept Surg, Gynecol Serv, New York, NY 10065 USA
[3] Univ Texas Houston, MD Anderson Canc Ctr, Dept Behav Sci, Houston, TX 77030 USA
关键词
Cancer; Vaginal Health; Survivorship; Sex; Estrogen Deprivation Symptoms in Cancer Survivors; QUALITY-OF-LIFE; INTRAVAGINAL DEHYDROEPIANDROSTERONE PRASTERONE; REDUCING SALPINGO-OOPHORECTOMY; FEMALE SEXUAL DYSFUNCTION; BREAST-CANCER; POSTMENOPAUSAL WOMEN; OVARIAN-CANCER; MENOPAUSAL SYMPTOMS; PSYCHOEDUCATIONAL INTERVENTION; HORMONE-THERAPY;
D O I
10.1111/j.1743-6109.2010.01988.x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Introduction. With the population of cancer survivors nearing 12 million, an ever-increasing number of women will face vaginal health issues related to their disease and/or treatment. Abrupt menopause triggered by cancer treatment, for example, can cause intense and prolonged estrogen deprivation symptoms, including vaginal dryness and discomfort. Simple strategies to promote vaginal health are available. Aims. To provide a comprehensive overview of vaginal health issues caused by estrogen deprivation in female cancer patients/survivors and provide recommendations to identify, treat, and promote vaginal health. Methods. We describe a treatment algorithm, based on scientific literature and supported by clinical experience, found to be effective in treating these patients at two major cancer centers. We also provide examples of handouts for patient education on vaginal health promotion. Main Outcome Measures. Evidence-based medicine and psychosocial literature, in addition to clinical experience at two major cancer centers. Results. Simple, non-hormonal interventions for sexual dysfunction are often overlooked. Several studies show that education on vaginal lubricants, moisturizers, and dilator use (as needed) can decrease the morbidity of vaginal atrophy. These studies also provide support for our clinical treatment recommendations. Our goal in this article is to increase awareness of these strategies and to provide assistance to general gynecologists and oncologists caring for cancer patients and survivors. Conclusions. Dedicating a small amount of time to educate female cancer survivors about methods to promote vaginal health can result in the reduction or elimination of vaginal discomfort. Non-hormonal vaginal health strategies often appear sufficient to remedy these issues. However, large randomized trials are needed, varying the format and components of the treatment program and exploring efficacy in various groups of female cancer survivors. Carter J, Goldfrank D, and Schover LR. Simple strategies for vaginal health promotion in cancer survivors. J Sex Med 2011;8:549-559.
引用
收藏
页码:549 / 559
页数:11
相关论文
共 88 条
[1]   Sexual activity and function in middle-aged and older women [J].
Addis, Ilana B. ;
Van den Eeden, Stephen K. ;
Wassel-Fyr, Christina L. ;
Vittinghoff, Eric ;
Brown, Jeanette S. ;
Thom, David H. .
OBSTETRICS AND GYNECOLOGY, 2006, 107 (04) :755-764
[2]   Sexual dysfunction after premenopausal Stage I and II breast cancer: Do androgens play a role? [J].
Alder, Judith ;
Zanetti, Rosanna ;
Wight, Edward ;
Urech, Corinne ;
Fink, Nadine ;
Bitzer, Johannes .
JOURNAL OF SEXUAL MEDICINE, 2008, 5 (08) :1898-1906
[3]   Effects of conjugated, equine estrogen in postmenopausal women with hysterectomy - The women's health initiative randomized controlled trial [J].
Anderson, GL ;
Limacher, M ;
Assaf, AR ;
Bassford, T ;
Beresford, SAA ;
Black, H ;
Bonds, D ;
Brunner, R ;
Brzyski, R ;
Caan, B ;
Chlebowski, R ;
Curb, D ;
Gass, M ;
Hays, J ;
Heiss, G ;
Hendrix, S ;
Howard, BV ;
Hsia, J ;
Hubbell, A ;
Jackson, R ;
Johnson, KC ;
Judd, H ;
Kotchen, JM ;
Kuller, L ;
LaCroix, AZ ;
Lane, D ;
Langer, RD ;
Lasser, N ;
Lewis, CE ;
Manson, J ;
Margolis, K ;
Ockene, J ;
O'Sullivan, MJ ;
Phillips, L ;
Prentice, RL ;
Ritenbaugh, C ;
Robbins, J ;
Rossouw, JE ;
Sarto, G ;
Stefanick, ML ;
Van Horn, L ;
Wactawski-Wende, J ;
Wallace, R ;
Wassertheil-Smoller, S .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 291 (14) :1701-1712
[4]   Longitudinal changes in sexual functioning as women transition through menopause: results from the Study of Women's Health Across the Nation [J].
Avis, Nancy E. ;
Brockwell, Sarah ;
Randolph, John F., Jr. ;
Shen, Shunhua ;
Cain, Virginia S. ;
Ory, Marcia ;
Greendale, Gail A. .
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2009, 16 (03) :442-452
[5]   The role of local vaginal estrogen for treatment of vaginal atrophy in postmenopausal women: 2007 position statement of The North American Menopause Society [J].
Bachmann, Gloria A. ;
Johnston, Shawna L. ;
Kessel, Bruce ;
Knobf, M. Tish ;
Stewart, Elizabeth G. .
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2007, 14 (03) :357-371
[6]   Climacteric symptoms in women undergoing risk-reducing bilateral salpingo-oophorectomy [J].
Benshushan, A. ;
Rojansky, N. ;
Chaviv, M. ;
Arbel-Alon, S. ;
Benmeir, A. ;
Imbar, T. ;
Brzezinski, A. .
CLIMACTERIC, 2009, 12 (05) :404-409
[7]   Vaginal changes and sexuality in women with a history of cervical cancer [J].
Bergmark, K ;
Åvall-Lundqvist, E ;
Dickman, PW ;
Henningsohn, L ;
Steineck, G .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (18) :1383-1389
[8]   Seeking help for sexual function complaints: what gynecologists need to know about the female patient's experience [J].
Berman, L ;
Berman, J ;
Felder, S ;
Pollets, D ;
Chhabra, S ;
Miles, M ;
Powell, JA .
FERTILITY AND STERILITY, 2003, 79 (03) :572-576
[9]   Menopause after breast cancer: a survey on breast cancer survivors [J].
Biglia, N ;
Cozzarella, M ;
Cacciari, F ;
Ponzone, R ;
Roagna, R ;
Maggiorotto, F ;
Sismondi, P .
MATURITAS, 2003, 45 (01) :29-38
[10]   A new non-pharmacological vacuum therapy for female sexual dysfunction [J].
Billups, KL ;
Berman, L ;
Berman, J ;
Metz, ME ;
Glennon, ME ;
Goldstein, I .
JOURNAL OF SEX & MARITAL THERAPY, 2001, 27 (05) :435-441