Methylnaltrexone (Relistor®) does not impact opioid-mediated analgesia at therapeutic doses

被引：1
作者：
Moss, Jonathan [1 ]
Paterson, Craig [2 ]
机构：
[1] Univ Chicago, Dept Anesthesia & Crit Care, 5841 S Maryland Ave,MC 4028, Chicago, IL 60637 USA
[2] Salix Pharmaceut Inc, Raleigh, NC USA
来源：
PAIN | 2014年 / 155卷 / 12期
关键词：
INDUCED CONSTIPATION; SUBCUTANEOUS METHYLNALTREXONE;
D O I：
10.1016/j.pain.2014.08.016
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
引用
收藏
页码：2722 / 2722
页数：1
相关论文
共 6 条
[1]   Subcutaneous methylnaltrexone for treatment of acute opioid-induced constipation: Phase 2 study in rehabilitation after orthopedic surgery [J].
Anissian, Lucas ;
Schwartz, Harry W. ;
Vincent, Kevin ;
Vincent, Heather K. ;
Carpenito, Jennifer ;
Stambler, Nancy ;
Ramakrishna, Tage .
JOURNAL OF HOSPITAL MEDICINE, 2012, 7 (02) :67-72
[2]   Peripheral opioid receptor blockade increases postoperative morphine demands-A randomized, double-blind, placebo-controlled trial [J].
Jagla, Christina ;
Martus, Peter ;
Stein, Christoph .
PAIN, 2014, 155 (10) :2056-2062
[3]   Subcutaneous Methylnaltrexone for Treatment of Opioid-Induced Constipation in Patients With Chronic, Nonmalignant Pain: A Randomized Controlled Study [J].
Michna, Edward ;
Blonsky, E. Richard ;
Schulman, Seth ;
Tzanis, Evan ;
Manley, Amy ;
Zhang, Haiying ;
Iyer, Shrividya ;
Randazzo, Bruce .
JOURNAL OF PAIN, 2011, 12 (05) :554-562
[4]  
Slatkin Neal, 2009, J Support Oncol, V7, P39
[5]   Methylnaltrexone for opioid-induced constipation in advanced illness [J].
Thomas, Jay ;
Karver, Sloan ;
Cooney, Gail Austin ;
Chamberlain, Bruce H. ;
Watt, Charles Kevin ;
Slatkin, Neal E. ;
Stambler, Nancy ;
Kremer, Alton B. ;
Israel, Robert J. .
NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (22) :2332-2343
[6]   Safety and Efficacy of Methylnaltrexone in Shortening the Duration of Postoperative Ileus Following Segmental Colectomy: Results of Two Randomized, Placebo-Controlled Phase 3 Trials [J].
Yu, Chang Sik ;
Chun, Ho-Kyung ;
Stambler, Nancy ;
Carpenito, Jennifer ;
Schulman, Seth ;
Tzanis, Evan ;
Randazzo, Bruce .
DISEASES OF THE COLON & RECTUM, 2011, 54 (05) :570-578
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