Cost-effectiveness of anesthesia maintained with sevoflurane or propofol with and without additional monitoring: a prospective, randomized controlled trial

被引:16
|
作者
Bocskai, Timea [1 ]
Loibl, Csaba [1 ]
Vamos, Zoltan [1 ]
Woth, Gabor [1 ]
Molnar, Tihamer [1 ]
Bogar, Lajos [1 ]
Lujber, Laszlo [2 ]
机构
[1] Univ Pecs, Med Sch, Dept Anaesthesiol & Intens Therapy, Ifjusag Str 13, H-7624 Pecs, Hungary
[2] Univ Pecs, Med Sch, Dept Otorhinolaryngol, Pecs, Hungary
来源
BMC ANESTHESIOLOGY | 2018年 / 18卷
关键词
Anesthesia; Patient safety; Cost; Bispectral index; Train-of-four; BISPECTRAL INDEX; NEUROMUSCULAR BLOCKADE; GENERAL-ANESTHESIA; SURGERY; RECOVERY; TIME; NARCOTREND; DEPTH;
D O I
10.1186/s12871-018-0563-z
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Background: We compared cost-effectiveness of anesthesia maintained with sevoflurane or propofol with and without additional monitoring, in the clinical setting of ear-nose-throat surgery. Methods: One hundred twenty adult patients were randomized to four groups. In groups SEVO and SEVO+ anesthesia was maintained with sevoflurane, in group SEVO+ with additional bispectral index (BIS) and train-of-four (TOF) monitoring. In groups PROP and PROP+ anesthesia was maintained with propofol, in group PROP+ with additional BIS and TOF monitoring. Results: Total cost of anesthesia per hour was greater in group SEVO+ compared to SEVO [& euro; 19.95(8.53) vs. 12.15(5. 32), p< 0.001], and in group PROP+ compared to PROP (& euro; 22.11(8.08) vs. 13.23(4.23), p< 0.001], Time to extubation was shorter in group SEVO+ compared to SEVO [11.1(4.7) vs. 14.5(3.9) min, p = 0.002], and in PROP+ compared to PROP [12.6(5.4) vs. 15.2(4.7) min, p< 0.001]. Postoperatively, arterial blood pressure returned to its initial values sooner in groups SEVO+ and PROP+. Conclusions: Our study demonstrated that the use of BIS and TOF monitoring decreased the total cost of anesthesia drugs and hastened postoperative recovery. However, in our circumstances, these were associated with higher disposables costs. Detailed cost analysis and further investigations are needed to identify patient populations who would benefit most from additional monitoring. Trial registration: ClimcaiTrials.gov, NCT02920749. Retrospectively registered (date of registration September 2016).
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页数:8
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