Intracranial aneurysms are abnormal enlargement in the walls of cerebral arteries. The rupture of aneurysms is the leading cause of subarachnoid hemorrhage (SAH), with a high mortality and morbidity rate. A majority of saccular cerebral aneurysms occur at sites of arterial bifurcations. However, a good percentage of aneurysms are curvature induced and are found along the cavernous arterial segment. The occurrence of such non branching aneurysms, clinically called dorsal aneurysms, can be related to the increased wall shear stress at the curved arteries. The rupture of aneurysms usually occurs at the dome region, which is subjected to reduced wall shear stress (wss) owing to low re-circulating flow. Hence it is important to understand the impact of arterial curvature on the WSS distribution along the dome of aneurysms. Previously, studies have not taken into account the aspect of low WSS along the dome region. In the present 3-d computational fluid dynamic approach, we investigate the impact of varying arterial curvature on spherical dorsal aneurysms. The primary velocity patterns, the WSS distribution along the dome of the aneurysm and the area of increased WSS have been quantified for steady flow conditions.
机构:
Tufts Med Ctr, Dept Neurosurg, Cerebrovasc & Endovasc Div, Boston, MA 02111 USA
Tufts Univ, Sch Med, Boston, MA 02111 USATufts Med Ctr, Dept Neurosurg, Cerebrovasc & Endovasc Div, Boston, MA 02111 USA
Kadasi, Laith M.
Dent, Walter C.
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机构:
Tufts Med Ctr, Dept Neurosurg, Cerebrovasc & Endovasc Div, Boston, MA 02111 USATufts Med Ctr, Dept Neurosurg, Cerebrovasc & Endovasc Div, Boston, MA 02111 USA
Dent, Walter C.
Malek, Adel M.
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机构:
Tufts Med Ctr, Dept Neurosurg, Cerebrovasc & Endovasc Div, Boston, MA 02111 USA
Tufts Univ, Sch Med, Boston, MA 02111 USATufts Med Ctr, Dept Neurosurg, Cerebrovasc & Endovasc Div, Boston, MA 02111 USA
机构:
Methodist Hosp, Neurol Inst, Dept Neurosurg, Houston, TX 77030 USA
Cornell Univ, Weil Med Coll, New York, NY 10021 USAMethodist Hosp, Neurol Inst, Dept Neurosurg, Houston, TX 77030 USA
机构:
Tufts Med Ctr, Dept Neurosurg, Cerebrovasc & Endovasc Div, Boston, MA 02111 USA
Tufts Univ, Sch Med, Boston, MA 02111 USATufts Med Ctr, Dept Neurosurg, Cerebrovasc & Endovasc Div, Boston, MA 02111 USA
Kadasi, Laith M.
Dent, Walter C.
论文数: 0引用数: 0
h-index: 0
机构:
Tufts Med Ctr, Dept Neurosurg, Cerebrovasc & Endovasc Div, Boston, MA 02111 USATufts Med Ctr, Dept Neurosurg, Cerebrovasc & Endovasc Div, Boston, MA 02111 USA
Dent, Walter C.
Malek, Adel M.
论文数: 0引用数: 0
h-index: 0
机构:
Tufts Med Ctr, Dept Neurosurg, Cerebrovasc & Endovasc Div, Boston, MA 02111 USA
Tufts Univ, Sch Med, Boston, MA 02111 USATufts Med Ctr, Dept Neurosurg, Cerebrovasc & Endovasc Div, Boston, MA 02111 USA
机构:
Methodist Hosp, Neurol Inst, Dept Neurosurg, Houston, TX 77030 USA
Cornell Univ, Weil Med Coll, New York, NY 10021 USAMethodist Hosp, Neurol Inst, Dept Neurosurg, Houston, TX 77030 USA