Enterovirus and parechovirus infection in children: a brief overview

被引：138
作者：
de Crom, S. C. M. [1 ,2 ]
Rossen, J. W. A. [3 ]
van Furth, A. M. [4 ]
Obihara, C. C. [2 ]
机构：
[1] St Elizabeth Hosp, Dept Pediat, Tilburg, Netherlands
[2] Maastricht Univ, Med Ctr, Dept Pediat, POB 5800, NL-6202 AZ Maastricht, Netherlands
[3] Univ Groningen, Univ Med Ctr Groningen, Dept Med Microbiol, Groningen, Netherlands
[4] Vrije Univ Amsterdam Med Ctr, Dept Pediat Infect Dis Immunol & Rheumatol, Amsterdam, Netherlands
来源：
EUROPEAN JOURNAL OF PEDIATRICS | 2016年 / 175卷 / 08期
关键词：
Enterovirus; Parechovirus; Overview; Children; Infection; NERVOUS-SYSTEM INFECTIONS; POLYMERASE-CHAIN-REACTION; REAL-TIME PCR; ASEPTIC-MENINGITIS; CEREBROSPINAL-FLUID; PICORNAVIRUS GROUP; HIGH PREVALENCE; YOUNG-CHILDREN; INFANTS; DIAGNOSIS;
D O I：
10.1007/s00431-016-2725-7
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Enterovirus and parechovirus are a frequent cause of infection in children. This review is an overview of what is known from enterovirus and parechovirus infection in children and contains information about the epidemiology, pathogenesis, clinical presentation, diagnosis, treatment, and prognosis of enterovirus and parechovirus infection in children. Conclusions: EV and HPeV infections are a frequent cause of infection in childhood. The clinical presentation is diverse. RT-qPCR is the best way to detect an EV or HPeV. Cerebrospinal fluid, blood and feces have the highest sensitivity for detecting an EV or HPeV. There is no treatment for EV and HPeV infections. Two vaccines against EV 71 are just licensed in China and will be available on the private market. Little is known about the prognosis of EV and HPeV infections.
引用
收藏
页码：1023 / 1029
页数：7
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