Total syntheses of marine polycyclic ethers

被引:335
作者
Nakata, T [1 ]
机构
[1] Tokyo Univ Sci, Dept Chem, Shinjuku Ku, Tokyo 1628601, Japan
关键词
D O I
10.1021/cr040627q
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A review of the total synthesis of marine polycyclic ethers by several synthetic organic chemists who have extensively studied the development of new strategies and efficient methodologies for the construction of ether rings and their application is presented. The intensive endeavors of these chemists have accumulated many efficient strategies and useful methods for construction of various types of polycycling ether ring systems. In addition to the total landmark syntheses of brevetoxin-B (BTX-B) and BTX-A, recent remarkable progress in synthetic organic chemistry has completed efficient syntheses of marine polyethers, including BTX-B, ciguatoxin CTX3C, gambierol and gymnocin-A.
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页码:4314 / 4347
页数:34
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