Polyketides from the marine sponge Plakortis angulospiculatus

被引：0

作者：

Epifanio, RD ^{[1
]}

Pinheiro, LS ^{[1
]}

Alves, NC ^{[1
]}

机构：

[1] Univ Fed Fluminense, Inst Quim, Ctr, Dept Quim Organ, BR-24020005 Niteroi, RJ, Brazil

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2005年 / 16卷 / 6B期

关键词：

Plakortis angulospiculatus; brine shrimp assay; antibacterial; polyketide;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Organic extracts of the marine sponge Plakortis angulospiculatus were studied from two different collections from Pernambuco State, Brazil. Bioautography with opportunistic marine pathogens, with results from the brine shrimp lethality assay, were used to guide the purification of the known furanylidenic methyl ester 1 and two new derivatives 2 and 3. The structures were elucidated by spectroscopic methods and by selective reduction of 3 into 2.

引用

页码：1367 / 1371

页数：5

共 15 条

[1] Marine natural products [J].

Blunt, JW ;

Copp, BR ;

Munro, MHG ;

Northcote, PT ;

Prinsep, MR .

NATURAL PRODUCT REPORTS, 2004, 21 (01) :1-49

[2] Comparison of anti-predatory defenses of Red Sea and Caribbean sponges. I. Chemical defense [J].

Burns, E ;

Ifrach, I ;

Carmeli, S ;

Pawlik, JR ;

Ilan, M .

MARINE ECOLOGY PROGRESS SERIES, 2003, 252 :105-114

[3] Metabolites from the sponge Plakortis simplex.: Determination of absolute stereochemistry of plakortin.: Isolation and stereostructure of three plakortin related compounds [J].

Cafieri, F ;

Fattorusso, E ;

Taglialatela-Scafati, O ;

Ianaro, A .

TETRAHEDRON, 1999, 55 (22) :7045-7056

[4] Antileishmanial cyclic peroxides from the Palauan sponge Plakortis aff. angulospiculatus [J].

Compagnone, RS ;

Piña, IC ;

Rangel, HR ;

Dagger, F ;

Suárez, AI ;

Reddy, MVR ;

Faulkner, DJ .

TETRAHEDRON, 1998, 54 (13) :3057-3068

[5] The sesterterpene variabilin as a fish-predation deterrent in the western Atlantic sponge Ircinia strobilina [J].

Epifanio, RD ;

Gabriel, R ;

Martins, DL ;

Muricy, G .

JOURNAL OF CHEMICAL ECOLOGY, 1999, 25 (10) :2247-2254

[6] Antimicrobial activity of extracts of Caribbean gorgonian corals [J].

Jensen, PR ;

Harvell, CD ;

Wirtz, K ;

Fenical, W .

MARINE BIOLOGY, 1996, 125 (02) :411-419

[7] Effects of Caribbean sponge extracts on bacterial attachment [J].

Kelly, SR ;

Jensen, PR ;

Henkel, TP ;

Fenical, W ;

Pawlik, JR .

AQUATIC MICROBIAL ECOLOGY, 2003, 31 (02) :175-182

[8] BRINE SHRIMP - A CONVENIENT GENERAL BIOASSAY FOR ACTIVE-PLANT CONSTITUENTS [J].

MEYER, BN ;

FERRIGNI, NR ;

PUTNAM, JE ;

JACOBSEN, LB ;

NICHOLS, DE ;

MCLAUGHLIN, JL .

PLANTA MEDICA, 1982, 45 (01) :31-34

[9] Taxonomy of Plakortis and Plakinastrella (Demospongiae: Plakinidae) from oceanic islands off north-eastern Brazil, with description of three new species [J].

Moraes, FC ;

Muricy, G .

JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM, 2003, 83 (02) :385-397

[10]

Muricy Guilherme, 1998, Revista Brasileira de Oceanografia, V46, P213

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