Decoding the Noncoding Cancer Genome

被引：0

作者：

van Galen, Peter ^{[1
,2
,3
]}

机构：

[1] Brigham & Womens Hosp, Div Hematol, Boston, MA 02115 USA

[2] Harvard Med Sch, Dept Med, Boston, MA 02115 USA

[3] Broad Inst MIT & Harvard, Cambridge, MA 02142 USA

来源：

CANCER DISCOVERY | 2020年 / 10卷 / 05期

关键词：

TERT PROMOTER MUTATIONS; RECURRENT;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In this issue of Cancer Discovery, Li and colleagues provide a blueprint for the identification and functional validation of cancer-associated mutations in noncoding regions of the genome. Integration of whole-genome sequencing and high-throughput epigenome editing screens is starting to reveal the extent to which noncoding genetic lesions contribute to cancer.

引用

页码：646 / 647

页数：2

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