Acute Respiratory Distress Syndrome: Etiology, Pathogenesis, and Summary on Management

被引:111
作者
Kaku, Shawn [1 ]
Nguyen, Christopher D. [2 ]
Htet, Natalie N. [1 ]
Tutera, Dominic [2 ]
Barr, Juliana [1 ,3 ]
Paintal, Harman S. [2 ,3 ]
Kuschner, Ware G. [2 ,3 ]
机构
[1] Stanford Univ, Dept Anesthesiol Perioperat & Pain Med, Sch Med, Stanford, CA 94305 USA
[2] Stanford Univ, Dept Med, Div Pulm & Crit Care Med, Sch Med, Stanford, CA 94305 USA
[3] Vet Affairs Palo Alto Hlth Care Syst, Palo Alto, CA USA
关键词
acute respiratory distress syndrome; sepsis; aspiration; mechanical ventilation; critical care medicine; ACUTE LUNG INJURY; INHALED NITRIC-OXIDE; PRESSURE RELEASE VENTILATION; NEUROMUSCULAR BLOCKING-AGENTS; MESENCHYMAL STEM-CELLS; TIDAL VOLUME VENTILATION; END-EXPIRATORY PRESSURE; CRITICALLY-ILL PATIENTS; GAMMA-LINOLENIC ACID; EXTRACORPOREAL MEMBRANE-OXYGENATION;
D O I
10.1177/0885066619855021
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
The acute respiratory distress syndrome (ARDS) has multiple causes and is characterized by acute lung inflammation and increased pulmonary vascular permeability, leading to hypoxemic respiratory failure and bilateral pulmonary radiographic opacities. The acute respiratory distress syndrome is associated with substantial morbidity and mortality, and effective treatment strategies are limited. This review presents the current state of the literature regarding the etiology, pathogenesis, and management strategies for ARDS.
引用
收藏
页码:723 / 737
页数:15
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