Comparison of 18F-FDG PET and MRI in assessment of uterine smooth muscle tumors

被引:21
作者
Yoshida, Yoshio [1 ]
Kurokawa, Tetsuji [1 ]
Sawamura, Yoko [1 ]
Shinagawa, Akiko [1 ]
Tsujikawa, Tetsuya [2 ]
Okazawa, Hidehiko [2 ]
Tsuchida, Tatsuro [3 ]
Imamura, Yoshiaki [4 ]
Suganuma, Narufumi [5 ]
Kotsuji, Fumikazu [1 ]
机构
[1] Univ Fukui, Fac Med Sci, Dept Obstet & Gynecol, Yoshida, Fukui 9101193, Japan
[2] Univ Fukui, Fac Med Sci, Biomed Imaging Res Ctr, Fukui 9101193, Japan
[3] Univ Fukui, Fac Med Sci, Dept Radiol, Fukui 9101193, Japan
[4] Univ Fukui, Fac Med Sci, Dept Pathol, Fukui 9101193, Japan
[5] Univ Fukui, Fac Med Sci, Dept Int Social & Hlth Sci, Fukui 9101193, Japan
关键词
genitourinary; oncology; PET; MRI; PET/MRI; F-18-FDG-PET; uterine smooth muscle tumors;
D O I
10.2967/jnumed.107.047142
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The purpose of this study was to prospectively determine whether combined MRI and F-18-FDG PET is more accurate than MRI in assessing nonbenign uterine smooth muscle tumors (USMTs). Methods: Seventy patients (mean age, 49 +/- 10 y; range, 28-77 y) suspected of having nonbenign USMTs underwent both MRI and F-18-FDG PET before surgery. Results were evaluated using receiver-operating-characteristic (ROC) analyses and the Cochran Q test. Results: The area under the ROC curve for MRI with F-18-FDG PET was significantly higher than that for MRI (0.97 vs. 0.89, P < 0.05). Although multiple comparisons using the Cochran Q test were not significant, the sensitivity, specificity, and accuracy for MRI with F-18-FDG PET with probable nonbenign USMT cases considered to be positive were higher than those for MRI (93.3% vs. 73.3%; 92.7% vs. 85.5%; and 92.9% vs. 82.9%, respectively). Conclusion: MRI with F-18-FDG PET is useful in assessing nonbenign USMTs, as compared with MRI.
引用
收藏
页码:708 / 712
页数:5
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