Diversity-Oriented Synthesis of Biaryl Derivatives Using Cross-Enyne Metathesis, Diels-Alder Reaction, and Suzuki-Miyaura Cross-Coupling as Key Steps

被引:22
作者
Kotha, Sambasivarao [1 ]
Seema, Vittal [1 ]
机构
[1] Indian Inst Technol, Dept Chem, Bombay 400076, Maharashtra, India
关键词
biaryl derivatives; cross-enyne metathesis; Suzuki-Miyaura cross-coupling; diversity-oriented synthesis; RING-CLOSING METATHESIS; ORGANIC-SYNTHESIS; CLAISEN REARRANGEMENT; EFFICIENT SYNTHESIS; NATURAL-PRODUCTS; ACID; DESIGN; ALKYNE; HETEROCYCLES; MOLECULES;
D O I
10.1055/s-0030-1260315
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Biaryl derivatives have been prepared by utilizing cross-enyne metathesis, Diels-Alder reaction followed by aromatization. These biaryl derivatives are further functionalized via Suzuki-Miyaura cross-coupling reaction to generate functionalized terphenyl derivatives.
引用
收藏
页码:2329 / 2334
页数:6
相关论文
共 50 条
  • [41] Development of Highly Potent GAT1 Inhibitors: Synthesis of Nipecotic Acid Derivatives by Suzuki-Miyaura Cross-Coupling Reactions
    Petrera, Marilena
    Wein, Thomas
    Allmendinger, Lars
    Sindelar, Miriam
    Pabel, Joerg
    Hoefner, Georg
    Wanner, Klaus T.
    CHEMMEDCHEM, 2016, 11 (05) : 519 - 538
  • [42] Facile Synthesis of Highly Stable Gold Nanoparticles and Their Unexpected Excellent Catalytic Activity for Suzuki-Miyaura Cross-Coupling Reaction in Water
    Han, Jie
    Liu, Yan
    Guo, Rong
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (06) : 2060 - +
  • [43] Suzuki-Miyaura cross-coupling reaction in water: facile synthesis of (hetero) aryl uracil bases using potassiumorganotrifluoroborates under microwave irradiation.
    Savitha, Bhaskaran
    Sajith, Ayyiliath M.
    Reddy, Eeda Koti
    Kumar, C. S. Ananda
    Padusha, M. Syed Ali
    CHEMISTRYSELECT, 2016, 1 (15): : 4721 - 4725
  • [44] A Bulky Chiral N-Heterocyclic Carbene Palladium Catalyst Enables Highly Enantioselective Suzuki-Miyaura Cross-Coupling Reactions for the Synthesis of Biaryl Atropisomers
    Shen, Di
    Xu, Youjun
    Shi, Shi-Liang
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2019, 141 (37) : 14938 - 14945
  • [45] A convenient synthesis of 4(5)-(hetero)aryl-1H-imidazoles via microwave-assisted Suzuki-Miyaura cross-coupling reaction
    Vichier-Guerre, Sophie
    Dugue, Laurence
    Pochet, Sylvie
    TETRAHEDRON LETTERS, 2014, 55 (46) : 6347 - 6350
  • [46] Suzuki-Miyaura cross-coupling and ring-closing metathesis: a strategic combination to the synthesis of indeno[1,2-c]isoquinolin-5,11-diones
    Lebrun, Stephane
    Couture, Axel
    Deniau, Eric
    Grandclaudon, Pierre
    TETRAHEDRON LETTERS, 2011, 52 (13) : 1481 - 1484
  • [47] Dimerization of Aromatic Compounds Using Palladium-Carbon-Catalyzed Suzuki-Miyaura Cross-Coupling by One-Pot Synthesis
    Du, Fangyu
    Zhou, Qifan
    Liu, Dongdong
    Fang, Ting
    Shi, Yajie
    Du, Yang
    Chen, Guoliang
    SYNLETT, 2018, 29 (06) : 779 - 784
  • [48] A novel electromagnetic mill promoted mechanochemical solid-state Suzuki-Miyaura cross-coupling reaction using ultra-low catalyst loading
    Li, Xin
    Liu, Yunxia
    Zhang, Lizhi
    Dong, Yunhui
    Liu, Qing
    Zhang, Daopeng
    Chen, Lei
    Zhao, Zengdian
    Liu, Hui
    GREEN CHEMISTRY, 2022, 24 (15) : 6026 - 6035
  • [49] An Efficient and Reliable Catalyst System Using Hemilabile Aphos for B-Alkyl Suzuki-Miyaura Cross-Coupling Reaction with Alkenyl Halides
    Ye, Ning
    Dai, Wei-Min
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2013, 2013 (05) : 831 - 835
  • [50] Synthesis of a Fluorescent Solvatochromic Resin Using Suzuki-Miyaura Cross-Coupling and Its Optical Waveguide Spectra to Measure the Solvent Polarity on the Surface
    Otsuka, Yu
    Li, Guanglei
    Takahashi, Hiromi
    Satoh, Hisashi
    Yamada, Koji
    MATERIALS, 2020, 13 (20) : 1 - 10