How Ebola has been evolving in West Africa

被引：2
作者：
Liu, Si-Qing [1 ]
Rayner, Simon [1 ]
Zhang, Bo [1 ]
机构：
[1] Chinese Acad Sci, Wuhan Inst Virol, Key Lab Etiol & Biosafety Emerging & Highly Infec, Wuhan 430071, Peoples R China
来源：
TRENDS IN MICROBIOLOGY | 2015年 / 23卷 / 07期
关键词：
Ebola; evolution; nucleotide substitutions rate; West Africa; low variation; MOLECULAR EVOLUTION; 2014; OUTBREAK; VIRUS; SEQUENCES; ORIGIN;
D O I：
10.1016/j.tim.2015.05.003
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The ongoing Ebola outbreak in West Africa has generated fears of a global epidemic. Particularly, estimates of higher substitution rates have raised concerns about increased transmissibility or virulence. A recent study using a more comprehensive datasets demonstrates lower variation, highlighting the importance of representative datasets and limitations of computational modelling.
引用
收藏
页码：387 / 388
页数：2
相关论文
共 10 条
  • [1] Emergence of Zaire Ebola Virus Disease in Guinea
    Baize, Sylvain
    Pannetier, Delphine
    Oestereich, Lisa
    Rieger, Toni
    Koivogui, Lamine
    Magassouba, N'Faly
    Soropogui, Barre
    Sow, Mamadou Saliou
    Keita, Sakoba
    De Clerck, Hilde
    Tiffany, Amanda
    Dominguez, Gemma
    Loua, Mathieu
    Traore, Alexis
    Kolie, Moussa
    Malano, Emmanuel Roland
    Heleze, Emmanuel
    Bocquin, Anne
    Mely, Stephane
    Raoul, Herve
    Caro, Valerie
    Cadar, Daniel
    Gabriel, Martin
    Pahlmann, Meike
    Tappe, Dennis
    Schmidt-Chanasit, Jonas
    Impouma, Benido
    Diallo, Abdoul Karim
    Formenty, Pierre
    Van Herp, Michel
    Guenther, Stephan
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (15) : 1418 - 1425
  • [2] Recent common ancestry of Ebola Zaire virus found in a bat reservoir
    Biek, Roman
    Walsh, Peter D.
    Leroy, Eric M.
    Real, Leslie A.
    [J]. PLOS PATHOGENS, 2006, 2 (10) : 885 - 886
  • [3] Molecular Evolution of Viruses of the Family Filoviridae Based on 97 Whole-Genome Sequences
    Carroll, Serena A.
    Towner, Jonathan S.
    Sealy, Tara K.
    McMullan, Laura K.
    Khristova, Marina L.
    Burt, Felicity J.
    Swanepoel, Robert
    Rollin, Pierre E.
    Nichol, Stuart T.
    [J]. JOURNAL OF VIROLOGY, 2013, 87 (05) : 2608 - 2616
  • [4] Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
    Gire, Stephen K.
    Goba, Augustine
    Andersen, Kristian G.
    Sealfon, Rachel S. G.
    Park, Daniel J.
    Kanneh, Lansana
    Jalloh, Simbirie
    Momoh, Mambu
    Fullah, Mohamed
    Dudas, Gytis
    Wohl, Shirlee
    Moses, Lina M.
    Yozwiak, Nathan L.
    Winnicki, Sarah
    Matranga, Christian B.
    Malboeuf, Christine M.
    Qu, James
    Gladden, Adrianne D.
    Schaffner, Stephen F.
    Yang, Xiao
    Jiang, Pan-Pan
    Nekoui, Mahan
    Colubri, Andres
    Coomber, Moinya Ruth
    Fonnie, Mbalu
    Moigboi, Alex
    Gbakie, Michael
    Kamara, Fatima K.
    Tucker, Veronica
    Konuwa, Edwin
    Saffa, Sidiki
    Sellu, Josephine
    Jalloh, Abdul Azziz
    Kovoma, Alice
    Koninga, James
    Mustapha, Ibrahim
    Kargbo, Kandeh
    Foday, Momoh
    Yillah, Mohamed
    Kanneh, Franklyn
    Robert, Willie
    Massally, James L. B.
    Chapman, Sinead B.
    Bochicchio, James
    Murphy, Cheryl
    Nusbaum, Chad
    Young, Sarah
    Birren, BruceW.
    Grant, Donald S.
    Scheiffelin, John S.
    [J]. SCIENCE, 2014, 345 (6202) : 1369 - 1372
  • [5] Mutation rate and genotype variation of Ebola virus from Mali case sequences
    Hoenen, T.
    Safronetz, D.
    Groseth, A.
    Wollenberg, K. R.
    Koita, O. A.
    Diarra, B.
    Fall, I. S.
    Haidara, F. C.
    Diallo, F.
    Sanogo, M.
    Sarro, Y. S.
    Kone, A.
    Togo, A. C. G.
    Traore, A.
    Kodio, M.
    Dosseh, A.
    Rosenke, K.
    de Wit, E.
    Feldmann, F.
    Ebihara, H.
    Munster, V. J.
    Zoon, K. C.
    Feldmann, H.
    Sow, S.
    [J]. SCIENCE, 2015, 348 (6230) : 117 - 119
  • [6] Identifying the pattern of molecular evolution for Zaire ebolavirus in the 2014 outbreak in West Africa
    Liu, Si-Qing
    Deng, Cheng-Lin
    Yuan, Zhi-Ming
    Rayner, Simon
    Zhang, Bo
    [J]. INFECTION GENETICS AND EVOLUTION, 2015, 32 : 51 - 59
  • [7] Challenges in RNA virus bioinformatics
    Marz, Manja
    Beerenwinkel, Niko
    Drosten, Christian
    Fricke, Markus
    Frishman, Dmitrij
    Hofacker, Ivo L.
    Hoffmann, Dieter
    Middendorf, Martin
    Rattei, Thomas
    Stadler, Peter F.
    Toepfer, Armin
    [J]. BIOINFORMATICS, 2014, 30 (13) : 1793 - 1799
  • [8] Persistence and genetic stability of Ebola virus during the outbreak in Kikwit, Democratic Republic of the Congo, 1995
    Rodriguez, LL
    De Roo, A
    Guimard, Y
    Trappier, SG
    Sanchez, A
    Bressler, D
    Williams, AJ
    Rowe, AK
    Bertolli, J
    Khan, AS
    Ksiazek, TG
    Peters, CJ
    Nichol, ST
    [J]. JOURNAL OF INFECTIOUS DISEASES, 1999, 179 : S170 - S176
  • [9] The origin and evolution of Ebola and Marburg viruses
    Suzuki, Y
    Gojobori, T
    [J]. MOLECULAR BIOLOGY AND EVOLUTION, 1997, 14 (08) : 800 - 806
  • [10] Wave-like spread of Ebola Zaire
    Walsh, PD
    Biek, R
    Real, LA
    [J]. PLOS BIOLOGY, 2005, 3 (11) : 1946 - 1953
1