A life course approach to cognitive reserve: A model for cognitive aging and development?

被引：244
作者：
Richards, M
Deary, IJ
机构：
[1] Univ Edinburgh, Dept Psychol, Edinburgh EH8 9JZ, Midlothian, Scotland
[2] UCL, MRC, Natl Survey Hlth & Dev, London WC1E 6BT, England
来源：
ANNALS OF NEUROLOGY | 2005年 / 58卷 / 04期
关键词：
D O I：
10.1002/ana.20637
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The concept of reserve in neuroscience maintains that there are aspects of brain structure and function that can buffer the effects of neuropathology such that the greater the reserve, the more severe the pathology must be to cause functional impairment. This article provides a concise overview of structural and functional approaches to reserve and shows how reserve may be conceived as the sum of its lifetime input. In this context, reserve therefore provides an empirical yet general model of cognitive aging and development.
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页码：617 / 622
页数：6
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