Challenges of Pancreatic Cancer

被引：47

作者：

Dimastromatteo, Julien ^{[1
]}

Houghton, Jacob L. ^{[2
,3
]}

Lewis, Jason S. ^{[2
,3
]}

Kelly, Kimberly A. ^{[1
]}

机构：

[1] Univ Virginia, Dept Biomed Engn, Robert M Berne Cardiovasc Res Ctr, Charlottesville, VA 22908 USA

[2] Mem Sloan Kettering Canc Ctr, Dept Radiol, New York, NY 10021 USA

[3] Mem Sloan Kettering Canc Ctr, Program Mol Pharmacol & Chem, New York, NY 10021 USA

来源：

CANCER JOURNAL | 2015年 / 21卷 / 03期

基金：

美国国家卫生研究院;

关键词：

ENDOTHELIAL GROWTH-FACTOR; POSITRON-EMISSION-TOMOGRAPHY; TUMOR-GROWTH; FDG-PET; EXPRESSION; DIAGNOSIS; CA-19-9; PROTEIN; MICROBUBBLES; PROGNOSIS;

D O I：

10.1097/PPO.0000000000000109

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The development of novel molecular cancer imaging agents has considerably advanced in recent years. Numerous cancer imaging agents have demonstrated remarkable potential for aiding the diagnosis, staging, and treatment planning at the preclinical stage, which in turn has led to a number of agents being approved for human trials. Pancreatic ductal adenocarcinoma is currently the most deadly common carcinoma with an overall 5-year survival rate of about 6%. As detection technologies progress, the need for molecular imaging tools that will allow the diagnosis at an early stage will be crucial to improving patient outcomes. In this review, we will highlight agents that illuminate various cell populations that comprise the tumor: epithelial, endothelial, and stromal tumor cells.

引用

页码：188 / 193

页数：6

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