Microarrays and surface engineering for bioanalysis

被引:2
作者
Gao, H [1 ]
Guinchard, S [1 ]
Crevoisier, F [1 ]
Angeloni, S [1 ]
Sigrist, H [1 ]
机构
[1] CSEM SA, Ctr Suisse Electron & Microtech SA, CH-2007 Neuchatel, Switzerland
关键词
functional platform; microarray; photoimmobilization; proteomics; surface passivation;
D O I
10.2533/000942903777678731
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Molecular engineering and covalent immobilization of biomolecules on material surfaces whilst retaining specificity and biological functions is a major challenge in bioarray manufacturing and analysis. Photochemical functionalization of materials enables specific bioengineering and facile manufacturing of biotech products for microanalysis with concomitant surface passivation. Surfaces engineered with polysaccharides render materials hydrophilic, biocompatible and generally applicable for probe molecule immobilization. Products and procedures described support microanalytical investigations in all '-omics' domains.
引用
收藏
页码:651 / 654
页数:4
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