Role of Postchemotherapy Retroperitoneal Lymph Node Dissection in Advanced Germ Cell Tumors

被引：8
|
作者：
Nguyen, Carvell T. [1 ]
Stephenson, Andrew J. [1 ]
机构：
[1] Cleveland Clin, Glickman Urol & Kidney Inst, Ctr Urol Oncol, Cleveland, OH 44195 USA
来源：
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2011年 / 25卷 / 03期
关键词：
Testicular neoplasms; Neoplasms; Germ cell; Embryonal; Chemotherapy; Retroperitoneum; Lymph node excision; Neoplasm staging; NONSEMINOMATOUS TESTICULAR CANCER; EUROPEAN CONSENSUS CONFERENCE; POSITRON-EMISSION-TOMOGRAPHY; RESIDUAL MASSES; OUTCOME ANALYSIS; MALIGNANT-TRANSFORMATION; COMBINATION CHEMOTHERAPY; SURGICAL RESECTION; THORACIC MASSES; SALVAGE SURGERY;
D O I：
10.1016/j.hoc.2011.03.002
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Advanced germ cell tumors (GCTs) are curable with the appropriate integration of cisplatin-based chemotherapy and postchemotherapy surgical resection of residual masses. For men with retroperitoneal metastases, postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) is a vital component of this treatment algorithm. The rationale for PC-RPLND is based on the consistent 10% to 20% and 35% to 55% incidence of viable malignancy and teratoma, respectively. Prognostic factors and nomograms cannot predict the presence of necrosis with sufficient accuracy to obviate the need for PC-RPLND. This article reviews the indications, technique, and outcomes of PC-RPLND in the management of advanced GCT.
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收藏
页码：593 / +
页数：13
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