Baricitinib Reduces GlycA Levels in Phase 2 and Phase 3 Clinical Trials in Patients with Moderate to Severe Rheumatoid Arthritis

被引：0

作者：

Kremer, Joel ^{[1
]}

Emery, Paul ^{[2
]}

Connelly, Margery A. ^{[3
]}

Otvos, James D. ^{[4
]}

Zuckerman, Steven H. ^{[5
]}

Ruotolo, Giacomo ^{[5
]}

Chen, Lei ^{[5
]}

Issa, Maher ^{[5
]}

Macias, William L. ^{[5
]}

McInnes, Iain B. ^{[6
]}

机构：

[1] Albany Med Coll, Albany, NY 12208 USA

[2] Leeds MSK Biomed Chapel Allerton Hosp, Leeds, W Yorkshire, England

[3] Lab Corp Amer Holdings LabCorp, Morrisvile, NC USA

[4] Lab Corp Amer Holdings LabCorp, Morrisville, NC USA

[5] Eli Lilly & Co, Indianapolis, IN 46285 USA

[6] Univ Glasgow, Glasgow, Lanark, Scotland

来源：

ARTHRITIS & RHEUMATOLOGY | 2017年 / 69卷

关键词：

DISEASE;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

415

引用

页数：3

共 3 条

[1] Selective Inhibition of JAK1 and JAK2 Is Efficacious in Rodent Models of Arthritis: Preclinical Characterization of INCB028050 [J].

Fridman, Jordan S. ;

Scherle, Peggy A. ;

Collins, Robert ;

Burn, Timothy C. ;

Li, Yanlong ;

Li, Jun ;

Covington, Maryanne B. ;

Thomas, Beth ;

Collier, Paul ;

Favata, Margaret F. ;

Wen, Xiaoming ;

Shi, Jack ;

McGee, Ryan ;

Haley, Patrick J. ;

Shepard, Stacey ;

Rodgers, James D. ;

Yeleswaram, Swamy ;

Hollis, Greg ;

Newton, Robert C. ;

Metcalf, Brian ;

Friedman, Steven M. ;

Vaddi, Kris .

JOURNAL OF IMMUNOLOGY, 2010, 184 (09) :5298-5307

[2] GlycA Is a Novel Biomarker of Inflammation and Subclinical Cardiovascular Disease in Psoriasis [J].

Joshi, Aditya A. ;

Lerman, Joseph B. ;

Aberra, Tsion M. ;

Afshar, Mehdi ;

Teague, Heather L. ;

Rodante, Justin A. ;

Krishnamoorthy, Parasuram ;

Ng, Qimin ;

Aridi, Tarek Z. ;

Salahuddin, Taufiq ;

Natarajan, Balaji ;

Lockshin, Benjamin N. ;

Ahlman, Mark A. ;

Chen, Marcus Y. ;

Rader, Daniel J. ;

Reilly, Muredach P. ;

Remaley, Alan T. ;

Bluemke, David A. ;

Playford, Martin P. ;

Gelfand, Joel M. ;

Mehta, Nehal N. .

CIRCULATION RESEARCH, 2016, 119 (11) :1242-+

[3] Utility of a novel inflammatory marker, GlycA, for assessment of rheumatoid arthritis disease activity and coronary atherosclerosis [J].

Ormseth, Michelle J. ;

Chung, Cecilia P. ;

Oeser, Annette M. ;

Connelly, Margery A. ;

Sokka, Tuulikki ;

Raggi, Paolo ;

Solus, Joseph F. ;

Otvos, James D. ;

Stein, C. Michael .

ARTHRITIS RESEARCH & THERAPY, 2015, 17

← 1 →