Key Green Engineering Research Areas for Sustainable Manufacturing: A Perspective from Pharmaceutical and Fine Chemicals Manufacturers

被引:329
作者
Jimenez-Gonzalez, Concepcion [1 ]
Poechlauer, Peter [2 ]
Broxterman, Quirinus B. [3 ]
Yang, Bing-Shiou [4 ]
Ende, David Am [5 ]
Baird, James [6 ]
Bertsch, Carl [7 ]
Hannah, Robert E. [8 ]
Dell'Orco, Phil [9 ]
Noorrnan, Henk [10 ]
Yee, Sandy [11 ]
Reintjens, Raf [3 ]
Wells, Andrew [12 ]
Massonneau, Viviane [13 ]
Manley, Julie [14 ]
机构
[1] GlaxoSmithKline, Sustainabil & Environm, Res Triangle Pk, NC 27709 USA
[2] DSM Pharmaceut Prod, A-4021 Linz, Austria
[3] DSM Innovat Synth BV, NL-6160 MD Geleen, Netherlands
[4] Boehringer Ingelheim Pharmaceut Inc, Ridgefield, CT 06877 USA
[5] Pfizer Inc, Chem Res & Dev, Groton, CT 06340 USA
[6] AstraZeneca, Essential Safety, Hlth & Environm, Macclesfield, Cheshire, England
[7] Eli Lilly & Co, Chem Proc Res & Dev, Lilly Technol Ctr, Indianapolis, IN 46285 USA
[8] GlaxoSmithKline, Sustainabil & Environm, Philadelphia, PA USA
[9] GlaxoSmithKline, Res & Dev, Upper Merion, PA USA
[10] DSM Biotechnol Ctr, NL-2600 AK Delft, Netherlands
[11] Johnson & Johnson, Compliance & Environm Affairs EHS2, Global Pharma, Horsham, PA 19044 USA
[12] AstraZeneca, Pharmaceut Dev, Loughborough, Leics, England
[13] Merck MSD Mfg, F-43700 Zi De Blavozy, St Germain Lapr, France
[14] ACS Green Chem Inst, Washington, DC 20036 USA
关键词
LIFE-CYCLE ASSESSMENT; CHEMISTRY; BIOCATALYSIS; TOOLS;
D O I
10.1021/op100327d
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
In 2005, the American Chemical Society (ACS) Green Chemistry Institute (GCI) and global pharmaceutical companies established the ACS GCI Pharmaceutical Roundtable to encourage the integration of green chemistry and engineering into the pharmaceutical industry. The Roundtable developed a list of key research areas in green chemistry in 2007, which has served as a guide for focusing green chemistry research. Following that publication, the Roundtable companies have identified a list of the key green engineering research areas that is intended to be the required companion of the first list. This publication summarizes the process used to identify and agree on the top key green engineering research areas and describes these areas, highlighting their research challenges and opportunities for improvements from the perspective of the pharmaceutical industry.
引用
收藏
页码:900 / 911
页数:12
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