Natural Chalcones in Chinese Materia Medica: Licorice

被引：61

作者：

Wang, Danni ^{[1
]}

Liang, Jing ^{[2
]}

Zhang, Jing ^{[1
]}

Wang, Yuefei ^{[1
]}

Chai, Xin ^{[1
]}

机构：

[1] Tianjin Univ Tradit Chinese Med, Tianjin State Key Lab Modern Chinese Med, Tianjin 301617, Peoples R China

[2] Chengdu Univ Tradit Chinese Med, Sch Foreign Language, Chengdu 611137, Sichuan, Peoples R China

来源：

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2020年 / 2020卷

基金：

中国国家自然科学基金;

关键词：

NF-KAPPA-B; TOLL-LIKE RECEPTOR; GLYCYRRHIZA-URALENSIS; LICOCHALCONE-E; IN-VITRO; CARBON-TETRACHLORIDE; ANTIOXIDANT CONSTITUENTS; ANTIBACTERIAL ACTIVITY; ANTICANCER PROPERTIES; SIGNALING PATHWAYS;

D O I：

10.1155/2020/3821248

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Licorice is an important Chinese materia medica frequently used in clinical practice, which contains more than 20 triterpenoids and 300 flavonoids. Chalcone, one of the major classes of flavonoid, has a variety of biological activities and is widely distributed in nature. To date, about 42 chalcones have been isolated and identified from licorice. These chalcones play a pivotal role when licorice exerts its pharmacological effects. According to the research reports, these compounds have a wide range of biological activities, containing anticancer, anti-inflammatory, antimicrobial, antioxidative, antiviral, antidiabetic, antidepressive, hepatoprotective activities, and so on. This review aims to summarize structures and biological activities of chalcones from licorice. We hope that this work can provide a theoretical basis for the further studies of chalcones from licorice.

引用

页数：14

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