Issues in the Differential Diagnosis of Uterine Low-grade Endometrioid Carcinoma, Including Mixed Endometrial Carcinomas: Recommendations from the International Society of Gynecological Pathologists

被引：49

作者：

Rabban, Joseph T. ^{[1
]}

Gilks, C. Blake ^{[2
,3
]}

Malpica, Anais ^{[4
]}

Matias-Guiu, Xavier ^{[5
,6
]}

Mittal, Khush ^{[7
]}

Mutter, George L. ^{[8
]}

Oliva, Esther ^{[9
]}

Parkash, Vinita ^{[10
]}

Ronnett, Brigitte M. ^{[11
]}

Staats, Paul ^{[12
]}

Stewart, Colin J. R. ^{[13
,14
]}

McCluggage, W. Glenn ^{[15
]}

机构：

[1] Univ Calif San Francisco, Dept Pathol, 1825 4th St, San Francisco, CA 94158 USA

[2] Vancouver Gen Hosp, Dept Pathol & Lab Med, Vancouver, BC, Canada

[3] Univ British Columbia, Vancouver, BC, Canada

[4] Univ Texas MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA

[5] Univ Hosp Arnau de Vilanova, Dept Pathol, Lleida, Spain

[6] Univ Lleida, Univ Hosp Bellvitge, Dept Pathol, IRBLLEIDA,IDIBELL,CIBERONC, Lleida, Spain

[7] NYU, Dept Pathol, Langone Med Ctr, 550 1St Ave, New York, NY 10016 USA

[8] Brigham & Womens Hosp, Dept Pathol, 75 Francis St, Boston, MA 02115 USA

[9] Massachusetts Gen Hosp, Dept Pathol, Boston, MA 02114 USA

[10] Yale New Haven Med Ctr, Dept Pathol, 20 York St, New Haven, CT 06504 USA

[11] Johns Hopkins Med Inst, Dept Pathol, Baltimore, MD 21205 USA

[12] Univ Maryland, Sch Med, Dept Pathol, Baltimore, MD 21201 USA

[13] Univ Western Australia, Dept Histopathol, King Edward Mem Hosp, Perth, WA, Australia

[14] Univ Western Australia, Sch Womens & Infants Hlth, Perth, WA, Australia

[15] Royal Grp Hosp Trust, Dept Pathol, Belfast, Antrim, North Ireland

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY | 2019年 / 38卷 / 01期

关键词：

Endometrial cancer; Atypical hyperplasia; Serous carcinoma; Mixed carcinoma; PAPILLARY SEROUS CARCINOMA; UNDIFFERENTIATED CARCINOMA; PROTEIN EXPRESSION; MISMATCH REPAIR; P16; EXPRESSION; ADENOCARCINOMA; MARKERS; CARCINOSARCOMA; CRITERIA; CANCER;

D O I：

10.1097/PGP.0000000000000512

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

This article provides practical recommendations developed from the International Society of Gynecological Pathologists Endometrial Carcinoma Project to address 4 issues that may arise in the diagnosis of uterine corpus low-grade endometrioid carcinoma: (1) The distinction between atypical hyperplasia and low-grade endometrioid carcinoma. (2) The distinction between low-grade endometrioid carcinoma and serous carcinoma. (3) The distinction between corded and hyalinized or spindle cell variants of low-grade endometrioid carcinoma and carcinosarcoma. (4) The diagnostic criteria for mixed endometrial carcinomas, a rare entity that should be diagnosed only after exclusion of a spectrum of tumors including morphologic variants of endometrioid carcinoma, dedifferentiated endometrial carcinoma, carcinosarcoma, and endometrial carcinomas with ambiguous morphology.

引用

页码：S25 / S39

页数：15

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