Inactivation of a 25.5 μm Enterococcus faecalis biofilm by a room-temperature, battery-operated, handheld air plasma jet

被引:150
作者
Pei, X. [1 ]
Lu, X. [1 ]
Liu, J. [1 ]
Liu, D. [1 ]
Yang, Y. [1 ]
Ostrikov, K. [2 ,3 ]
Chu, Paul K. [4 ]
Pan, Y. [1 ]
机构
[1] Huazhong Univ Sci & Technol, State Key Lab Adv Electromagnet Engn & Technol, Wuhan 430074, Hubei, Peoples R China
[2] CSIRO Mat Sci & Engn, PNCA, Lindfield, NSW 2070, Australia
[3] Univ Sydney, Sch Phys, Sydney, NSW 2006, Australia
[4] City Univ Hong Kong, Dept Phys & Mat Sci, Kowloon, Hong Kong, Peoples R China
基金
高等学校博士学科点专项科研基金; 澳大利亚研究理事会;
关键词
D O I
10.1088/0022-3727/45/16/165205
中图分类号
O59 [应用物理学];
学科分类号
摘要
Effective biofilm inactivation using a handheld, mobile plasma jet powered by a 12V dc battery and operated in open air without any external gas supply is reported. This cold, room-temperature plasma is produced in self-repetitive nanosecond discharges with current pulses of similar to 100 ns duration, current peak amplitude of similar to 6mA and repetition rate of similar to 20 kHz. It is shown that the reactive plasma species penetrate to the bottom layer of a 25.5 mu m-thick Enterococcus faecalis biofilm and produce a strong bactericidal effect. This is the thickest reported biofilm inactivated using room-temperature air plasmas.
引用
收藏
页数:5
相关论文
共 16 条
  • [1] Degradation of Staphylococcus aureus bacteria by neutral oxygen atoms
    Cvelbar, U.
    Mozetic, M.
    Hauptman, N.
    Klanjsek-Gunde, M.
    [J]. JOURNAL OF APPLIED PHYSICS, 2009, 106 (10)
  • [2] The ecology, epidemiology and virulence of Enterococcus
    Fisher, Katie
    Phillips, Carol
    [J]. MICROBIOLOGY-SGM, 2009, 155 : 1749 - 1757
  • [3] The biofilm matrix
    Flemming, Hans-Curt
    Wingender, Jost
    [J]. NATURE REVIEWS MICROBIOLOGY, 2010, 8 (09) : 623 - 633
  • [4] Applied plasma medicine
    Fridman, Gregory
    Friedman, Gary
    Gutsol, Alexander
    Shekhter, Anatoly B.
    Vasilets, Victor N.
    Fridman, Alexander
    [J]. PLASMA PROCESSES AND POLYMERS, 2008, 5 (06) : 503 - 533
  • [5] Cold plasma selectivity and the possibility of a paradigm shift in cancer therapy
    Keidar, M.
    Walk, R.
    Shashurin, A.
    Srinivasan, P.
    Sandler, A.
    Dasgupta, S.
    Ravi, R.
    Guerrero-Preston, R.
    Trink, B.
    [J]. BRITISH JOURNAL OF CANCER, 2011, 105 (09) : 1295 - 1301
  • [6] Kong M.G., 2009, NEW J PHYS, V11, P1, DOI DOI 10.1088/1367-2630/11/11/115012
  • [7] Low-Temperature Plasmas for Medicine?
    Laroussi, Mounir
    [J]. IEEE TRANSACTIONS ON PLASMA SCIENCE, 2009, 37 (06) : 714 - 725
  • [8] He+O2+H2O plasmas as a source of reactive oxygen species
    Liu, D. X.
    Iza, F.
    Wang, X. H.
    Kong, M. G.
    Rong, M. Z.
    [J]. APPLIED PHYSICS LETTERS, 2011, 98 (22)
  • [9] Main Species and Physicochemical Processes in Cold Atmospheric-pressure He + O2 Plasmas
    Liu, Ding-Xin
    Rong, Ming-Zhe
    Wang, Xiao-Hua
    Iza, Felipe
    Kong, Michael G.
    Bruggeman, Peter
    [J]. PLASMA PROCESSES AND POLYMERS, 2010, 7 (9-10) : 846 - 865
  • [10] The roles of the various plasma agents in the inactivation of bacteria
    Lu, XinPei
    Ye, Tao
    Cao, YingGuang
    Sun, ZiYong
    Xiong, Qing
    Tang, ZhiYuan
    Xiong, ZhiLan
    Hu, Jing
    Jiang, ZhongHe
    Pan, Yuan
    [J]. JOURNAL OF APPLIED PHYSICS, 2008, 104 (05)