Tasnemoxides A-C, new cytotoxic cyclic norsesterterpene Peroxides from the red sea sponge Diacarnus erythraenus

被引：28

作者：

Youssef, DTA ^{[1
]}

机构：

[1] Suez Canal Univ, Fac Pharm, Dept Pharmacognosy, Ismailia 41522, Egypt

来源：

JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 01期

关键词：

D O I：

10.1021/np0340192

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Tasnemoxides A-C (1-3), three new cytotoxic cyclic norsestertepene peroxides, were isolated from the Red Sea sponge Diacarnus erythraenus, together with the known compound sigmoseeptrellin B (4). The structural determination of the isolated compounds was based on extensive 1D and 2D NMR studies and mass spectral determinations. Compounds 1-3 showed moderate cytotoxicity against three cancer cell lines.

引用

页码：112 / 114

页数：3

共 17 条

[1]

ALBERICCI M, 1979, TETRAHEDRON LETT, P2687

[2] CHEMICAL STUDIES OF MARINE-INVERTEBRATES .45. THE CHEMISTRY OF 3-NORSESTERTERPENE PEROXIDES FROM THE SPONGE SIGMOSCEPTRELLA-LAEVIS [J].

ALBERICCI, M ;

BRAEKMAN, JC ;

DALOZE, D ;

TURSCH, B .

TETRAHEDRON, 1982, 38 (13) :1881-1890

[3] 2 NEW NORSESTERTERPENE CYCLIC PEROXIDES FROM A MARINE SPONGE, MYCALE (CARMIA) CF SPONGIOSA [J].

CAPON, RJ .

JOURNAL OF NATURAL PRODUCTS, 1991, 54 (01) :190-195

[4] STRUCTURAL AND STEREOCHEMICAL STUDIES ON MARINE NORTERPENE CYCLIC PEROXIDES [J].

CAPON, RJ ;

MACLEOD, JK .

TETRAHEDRON, 1985, 41 (16) :3391-3404

[5] New types of potentially antimalarial agents:: Epidioxy-substituted norditerpene and norsesterpenes from the marine sponge Diacarnus levii [J].

D'Ambrosio, M ;

Guerriero, A ;

Deharo, E ;

Debitus, C ;

Munoz, V ;

Pietra, F .

HELVETICA CHIMICA ACTA, 1998, 81 (07) :1285-1292

[6] Antimalarial, antiviral, and antitoxoplasmosis norsesterterpene peroxide acids from the Red Sea sponge Diacarnus erythraeanus [J].

El Sayed, KA ;

Hamann, MT ;

Hashish, NE ;

Shier, WT ;

Kelly, M ;

Khan, AA .

JOURNAL OF NATURAL PRODUCTS, 2001, 64 (04) :522-524

[7] 2 NEW BIOACTIVE CYCLIC PEROXIDES FROM THE MARINE SPONGE PLAKORTIS-ANGULOSPICULATUS [J].

GUNASEKERA, SP ;

GUNASEKERA, M ;

GUNAWARDANA, GP ;

MCCARTHY, P ;

BURRES, N .

JOURNAL OF NATURAL PRODUCTS, 1990, 53 (03) :669-674

[8] Cyclic polyketide peroxides and acyclic diol analogues from the sponge Plakortis lita [J].

Harrison, B ;

Crews, P .

JOURNAL OF NATURAL PRODUCTS, 1998, 61 (08) :1033-1037

[9] NORSESTERTERPENE PEROXIDES FROM THE SPONGE LATRUNCULIA SP [J].

HE, HY ;

FAULKNER, DJ ;

LU, HSM ;

CLARDY, J .

JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (06) :2112-2115

[10]

KELLY M, 2002, SYSTEMA PORIFERA GUI, V1, P694

← 1 2 →