Nitric oxide, cytochrome-c oxidase and myoglobin

被引:167
作者
Brunori, M [1 ]
机构
[1] Univ Roma La Sapienza, Dept Biochem Sci, I-00185 Rome, Italy
关键词
D O I
10.1016/S0968-0004(00)01698-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Myoglobin,the monomeric haemoprotein expressed in red muscle, is reported in biochemistry and physiology textbooks to function as an intracellular oxygen carrier and oxygen reservoir. Here, Maurizio Brunori argues that myoglobin can also play the role of intracellular scavenger of nitric oxide, an inhibitor of mitochondrial cytochrome-e oxidase, thereby protecting respiration in the skeletal muscle and the heart.
引用
收藏
页码:21 / 23
页数:3
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