The experience of an emergency intensive care unit during the COVID-19 pandemic: A retrospective cohort study Emergency intensive care unit experiences due to COVID-19

被引:0
作者
Ramazan, Guven [1 ]
Basar, Cander [1 ]
Burcu, Genc Yavuz [2 ]
Ramazan, Unal [1 ]
Ertugrul, Ak [1 ]
Salih, Fettahoglu [1 ]
机构
[1] Univ Hlth Sci, Kanuni Training & Res Hosp, Dept Emergency Med, Atakent Mh Turgut Ozal Bulvari 46-1, TR-34303 Istanbul, Turkey
[2] Univ Hlth Sci, Haydarpasa Numune Training & Res Hosp, Dept Emergency Med, Istanbul, Turkey
来源
ANNALS OF CLINICAL AND ANALYTICAL MEDICINE | 2021年 / 12卷
关键词
COVID-19; Emergency Medicine; Intensive Care Unit; Mortality Rate; LENGTH-OF-STAY;
D O I
10.4328/ACAM.20622
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aim: The availability of an intensive care unit in the emergency departments (EDICU) is one of the most important issues discussed recently in terms of increasing the quality of emergency patient care. In this study, we aimed to investigate the clinical characteristics and factors affecting the mortality in patients with COVID-19. Material and Methods: This is a retrospective study of patients with COVID-19 hospitalized in EDICU. Patients were divided into mortality and survival groups, and the clinical characteristics of these groups were compared. Results: A total of 38 patients were included; 47.4% (n = 18) were in the survival group. Oxygen saturation level was significantly different between the mortality and survival groups [78.0% (63.7-83.0) vs 88.5% (81.5-93.2), p = 0.001). Patients in the mortality group had higher plasma levels of lactate dehydrogenase (LDH), procalcitonin, C-reactive protein (CRP), lactate, ferritin and D-dimer. Univariate regression analysis showed that oxygen saturation, LDH, CRP and endotracheal intubation (ETI) were significant markers in predicting mortality (p = 0.011, p = 0.035, p <0.001, respectively). A CRP level >= 91.9 mg/L predicts mortality with a sensitivity of 66.6% and a specificity of 80.0% (AUC: 0.781, 95% CI: 0.617- 0,898). Discussion: This study showed that oxygen saturation, ETI, LDH and CRP levels were significantly successful in predicting mortality. Therefore, early administration of antibiotherapy and timely use of ETI may increase the quality of patient care.
引用
收藏
页码:423 / 427
页数:5
相关论文
共 17 条
[1]   Covid-19 in Critically Ill Patients in the Seattle Region - Case Series [J].
Bhatraju, Pavan K. ;
Ghassemieh, Bijan J. ;
Nichols, Michelle ;
Kim, Richard ;
Jerome, Keith R. ;
Nalla, Arun K. ;
Greninger, Alexander L. ;
Pipavath, Sudhakar ;
Wurfel, Mark M. ;
Evans, Laura ;
Kritek, Patricia A. ;
West, T. Eoin ;
Luks, Andrew ;
Gerbino, Anthony ;
Dale, Chris R. ;
Goldman, Jason D. ;
O'Mahony, Shane ;
Mikacenic, Carmen .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (21) :2012-2022
[2]   Impact of delayed transfer of critically ill patients from the emergency department to the intensive care unit [J].
Chalfin, Donald B. ;
Trzeciak, Stephen ;
Likourezos, Antonios ;
Baumann, Brigitte M. ;
Dellinger, R. Phillip .
CRITICAL CARE MEDICINE, 2007, 35 (06) :1477-1483
[3]   COVID-19 outbreak control, example of ministry of health of Turkey [J].
Demirbilek, Yasemin ;
Pehlivanturk, Gulen ;
Ozguler, Zeynep Ozge ;
Alp Mese, Emine .
TURKISH JOURNAL OF MEDICAL SCIENCES, 2020, 50 :489-494
[4]   Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study [J].
Grasselli, Giacomo ;
Tonetti, Tommaso ;
Protti, Alessandro ;
Langer, Thomas ;
Girardis, Massimo ;
Bellani, Giacomo ;
Laffey, John ;
Carrafiello, Gianpaolo ;
Carsana, Luca ;
Rizzuto, Chiara ;
Zanella, Alberto ;
Scaravilli, Vittorio ;
Pizzilli, Giacinto ;
Grieco, Domenico Luca ;
Di Meglio, Letizia ;
de Pascale, Gennaro ;
Lanza, Ezio ;
Monteduro, Francesco ;
Zompatori, Maurizio ;
Filippini, Claudia ;
Locatelli, Franco ;
Cecconi, Maurizio ;
Fumagalli, Roberto ;
Nava, Stefano ;
Vincent, Jean-Louis ;
Antonelli, Massimo ;
Slutsky, Arthur S. ;
Pesenti, Antonio ;
Ranieri, V. Marco .
LANCET RESPIRATORY MEDICINE, 2020, 8 (12) :1201-1208
[5]   Association of an Emergency Department-Based Intensive Care Unit With Survival and Inpatient Intensive Care Unit Admissions [J].
Gunnerson, Kyle J. ;
Bassin, Benjamin S. ;
Havey, Renee A. ;
Haas, Nathan L. ;
Sozener, Cemal B. ;
Medlin, Richard P., Jr. ;
Gegenheimer-Holmes, Jennifer A. ;
Laurinec, Stephanie L. ;
Boyd, Caryn ;
Cranford, James A. ;
Whitmore, Sage P. ;
Hsu, Cindy H. ;
Khan, Reham ;
Vazirani, Neha N. ;
Maxwell, Stephen G. ;
Neumar, Robert W. .
JAMA NETWORK OPEN, 2019, 2 (07)
[6]   First COVID-19 sub-intensive respiratory unit in Europe: the Italian experience [J].
Henchi, Sonia ;
Conti, Clara Benedetta ;
Vanoni, Nicolo ;
Repossi, Alice Claudia ;
Cipolla, Giuseppe ;
Marra, Mirko ;
Esposti, Elena ;
Fiini, Michela ;
Cominesi, Irene Raimondi ;
Crepaldi, Monica ;
Scozzafava, Mariano .
MULTIDISCIPLINARY RESPIRATORY MEDICINE, 2020, 15
[7]   C-reactive protein, procalcitonin, D-dimer, and ferritin in severe coronavirus disease-2019: a meta-analysis [J].
Huang, Ian ;
Pranata, Raymond ;
Lim, Michael Anthonius ;
Oehadian, Amaylia ;
Alisjahbana, Bachti .
THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE, 2020, 14
[8]   Successful Treatment Strategy of Turkey Against Covid-19 Outbreak [J].
Kodaz, Hilmi .
EURASIAN JOURNAL OF MEDICINE AND ONCOLOGY, 2020, 4 (02) :177-178
[9]   Anatomy of resuscitative care unit: expanding the borders of traditional intensive care units [J].
Leibner, Evan ;
Spiegel, Rory ;
Hsu, Cindy H. ;
Wright, Brian ;
Bassin, Benjamin S. ;
Gunnerson, Kyle ;
O'Connor, James ;
Stein, Deborah ;
Weingart, Scott ;
Greenwood, John C. ;
Rubinson, Lewis ;
Menaker, Jay ;
Scalea, Thomas M. .
EMERGENCY MEDICINE JOURNAL, 2019, 36 (06) :364-368
[10]  
Matta SK, 2020, J INTENSIVE CRITICAL, V6, P7, DOI [10.36648/2471-8505.6.2.7, DOI 10.36648/2471-8505.6.2.7]