Synthesis and crystal structure of 4-(2-chlorophenyl)-6-methyl-5-ethoxycaronyl-3,4-dihydropyrimidin-2(H)-one under microwave irradiation

The title compound (C14H15ClN2O3) was synthesized by the reaction of 2-chlorobenzaldehyde, ethyl acetoacetate, urea and TsOH under microwave irradiation and its structure has been determined by single-crystal X-ray diffraction. The crystal is of triclinic, space group P(1) over bar with a = 7.688(1), b = 9.106(2), c = 11.412(2) Angstrom, alpha = 102.963(3), beta = 105.957(2), gamma = 102.484(2)degrees, V = 714.9(2) Angstrom(3), Z = 2, M-r = 294.73, D-c = 1.369 g/cm(3), mu = 0.276 mm(-1) and F(000)= 308. The structure was solved by direct methods and refined by full-matrix least-squares technique to the final R = 0.0845 and wR = 0.2092. X-ray analysis reveals that the dihedral angle between planes 1 (benzene ring) and 2(C(8)-C(9)-C(10)-N(2)) is 91.5degrees. The pyrimidine ring is in a boat configuration in the structure.