Application of double-balloon enteroscopy in jejunal diverticular bleeding

AIM: To evaluate the efficacy of endoscopic diagnosis and therapy for jejunal diverticular bleeding. METHODS: From January 2004 to September 2009, 154 patients underwent double-balloon enteroscopy (DBE) for obscure gastrointestinal bleeding. Ten consecutive patients with jejunal diverticula (5 males and 5 females) at the age of 68.7 +/- 2.1 years (range 1995 years) at Chang Gung Memorial Hospital, Academic Tertiary Referral Center, were enrolled in this study. RESULTS: Of the 10 patients, 5 had melena, 2 had hematochezia, 2 had both melena and hematochezia, 1 had anemia and dizziness. DBE revealed ulcers with stigmata of recent hemorrhage in 6 patients treated by injection of epinephrine diluted at 1:10000, Dieulafoy-like lesions in 4 patients treated by deploying hemoclips on the vessels, colonic diverticula in 2 patients, and duodenal diverticula in 3 patients, respectively. Of the 2 patients who underwent surgical intervention, 1 had a large diverticulum and was referred by the surgeon for DBE, 1 received endoscopic therapy but failed due to massive bleeding. One patient had a second DBE for recurrent hemorrhage 7 mo later, which was successfully treated with a repeat endoscopy. The mean follow-up time of patients was 14.7 +/- 7.8 mo. CONCLUSION: DBE is a safe and effective treatment modality for jejunal diverticular bleeding. (C) 2010 Baishideng. All rights reserved.