Cohort profile: prescriptions dispensed in the community linked to the national cancer registry in England

被引:18
作者
Henson, Katherine E. [1 ]
Brock, Rachael [1 ]
Shand, Brian [1 ]
Coupland, Victoria H. [1 ]
Elliss-Brookes, Lucy [1 ]
Lyratzopoulos, Georgios [1 ,2 ]
Godfrey, Philip [3 ]
Haigh, Abigail [3 ]
Hunter, Kelvin [4 ]
McCabe, Martin G. [1 ,5 ]
Mitchell, Graham [3 ]
Monckton, Nina [3 ]
Robson, Robert [3 ]
Round, Thomas [6 ]
Wong, Kwok [1 ]
Rashbass, Jem [1 ]
机构
[1] Publ Hlth England, Natl Canc Registrat & Anal Serv, London, England
[2] UCL, Dept Behav Sci & Hlth, ECHO Epidemiol Canc Healthcare & Outcomes Grp, London, England
[3] NHS Business Serv Author, NHS Prescript Serv, Newcastle Upon Tyne, Tyne & Wear, England
[4] Univ Cambridge, Addenbrookes Hosp, Dept Med, Cambridge, England
[5] Univ Manchester, Manchester Acad Hlth Sci Ctr, Inst Canc Sci, Core Technol Facil, Manchester, Lancs, England
[6] Kings Coll London, Dept Primary Care & Publ Hlth Sci, London, England
关键词
oncology; epidemiology; primary care; health informatics; DATA RESOURCE PROFILE; GENERAL-PRACTICE; DIAGNOSIS;
D O I
10.1136/bmjopen-2017-020980
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose The linked prescriptions cancer registry data resource was set up to extend our understanding of the pathway for patients with cancer past secondary care into the community, to ultimately improve patient outcomes. Participants The linked prescriptions cancer registry data resource is currently available for April to July 2015, for all patients diagnosed with cancer in England with a dispensed prescription in that time frame. The dispensed prescriptions data are collected by National Health Service (NHS) Prescription Services, and the cancer registry data are processed by Public Health England. All data are routine healthcare data, used for secondary purposes, linked using a pseudonymised version of the patient's NHS number and date of birth. Detailed demographic and clinical information on the type of cancer diagnosed and treatment is collected by the cancer registry. The dispensed prescriptions data contain basic demographic information, geography measures of the dispensed prescription, drug information (quantity, strength and presentation), cost of the drug and the date that the dispensed prescription was submitted to NHS Business Services Authority. Findings to date Findings include a study of end of life prescribing in the community among patients with cancer, an investigation of repeat prescriptions to derive measures of prior morbidity status in patients with cancer and studies of prescription activity surrounding the date of cancer diagnosis. Future plans This English linked resource could be used for cancer epidemiological studies of diagnostic pathways, health outcomes and inequalities; to establish primary care comorbidity indices and for guideline concordance studies of treatment, particularly hormonal therapy, as a major treatment modality for breast and prostate cancer which has been largely delivered in the community setting for a number of years.
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页数:9
相关论文
共 17 条
[1]   Data Resource Profile: The Scottish National Prescribing Information System (PIS) [J].
Alvarez-Madrazo, Samantha ;
McTaggart, Stuart ;
Nangle, Clifford ;
Nicholson, Elizabeth ;
Bennie, Marion .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2016, 45 (03) :714-715F
[2]  
[Anonymous], 2014, The UK private health market
[3]  
Department of Health, INFORM GOVERNANCE RE
[4]  
European Union, 2018, GEN DAT PROT REG
[5]   General practice consultations, diagnostic investigations, and prescriptions in the year preceding a lung cancer diagnosis [J].
Guldbrandt, Louise M. ;
Moller, Henrik ;
Jakobsen, Erik ;
Vedsted, Peter .
CANCER MEDICINE, 2017, 6 (01) :79-88
[6]   Increased diagnostic activity in general practice during the year preceding colorectal cancer diagnosis [J].
Hansen, Pernille Libach ;
Hjertholm, Peter ;
Vedsted, Peter .
INTERNATIONAL JOURNAL OF CANCER, 2015, 137 (03) :615-624
[7]  
Henson K, 2017, 2017 ANN C N AM ASS
[8]   Data Resource Profile: Hospital Episode Statistics Admitted Patient Care (HES APC) [J].
Herbert, Annie ;
Wijlaars, Linda ;
Zylbersztejn, Ania ;
Cromwell, David ;
Hardelid, Pia .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2017, 46 (04) :1093-+
[9]   Data Resource Profile: Clinical Practice Research Datalink (CPRD) [J].
Herrett, Emily ;
Gallagher, Arlene M. ;
Bhaskaran, Krishnan ;
Forbes, Harriet ;
Mathur, Rohini ;
van Staa, Tjeerd ;
Smeeth, Liam .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2015, 44 (03) :827-836
[10]  
Johannesdottir Sigrun Alba, 2012, Clin Epidemiol, V4, P303, DOI 10.2147/CLEP.S37587