Capecitabine cardiac toxicity presenting as effort angina: a case report

被引：20
作者：
Lestuzzi, Chiara [1 ]
Crivellari, Diana [2 ]
Rigo, Fausto [3 ]
Viel, Elda
Meneguzzo, Nereo
机构：
[1] IRCCS, UO Cardiol, Ctr Riferimento Oncol, Cardiol Unit,Natl Canc Inst, I-33081 Aviano, Pordenone, Italy
[2] IRCCS, Dept Oncol, Ctr Riferimento Oncol, Natl Canc Inst, I-33081 Aviano, Pordenone, Italy
[3] Osped Angelo, Dept Cardiol, Venice, Italy
来源：
JOURNAL OF CARDIOVASCULAR MEDICINE | 2010年 / 11卷 / 09期
关键词：
angina; capecitabine; cardiotoxicity; CONTINUOUS-INFUSION; CARDIOTOXICITY; 5-FLUOROURACIL; FLUOROURACIL;
D O I：
10.2459/JCM.0b013e328332e873
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report a case of capecitabine-induced cardiotoxicity (effort angina) in a woman with metastatic breast carcinoma. Due to cancer progression, rechallenge of therapy with capecitabine was attempted, using several strategies in order to prevent cardiotoxicity. The most (even if not fully) effective strategy was reducing capecitabine dosage together with nitrates, calcium-channel blockers and trimetazidine therapy. J Cardiovasc Med 11:700-703 (C) 2010 Italian Federation of Cardiology.
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收藏
页码：700 / 703
页数：4
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