Effect of Gastric Bypass on Vitamin D and Secondary Hyperparathyroidism

被引：48

作者：

Signori, Carina ^{[2
,3
,4
]}

Zalesin, Kerstyn C. ^{[1
,2
,3
,4
]}

Franklin, Barry ^{[2
,3
,4
]}

Miller, Wendy L. ^{[2
,3
,4
]}

McCullough, Peter A. ^{[2
,3
,4
]}

机构：

[1] William Beaumont Hosp, Dept Nutr & Prevent Med, Div Internal Med, Royal Oak, MI 48073 USA

[2] William Beaumont Hosp, Dept Med, Div Cardiol, Royal Oak, MI 48073 USA

[3] William Beaumont Hosp, Dept Med, Div Nutr, Royal Oak, MI 48073 USA

[4] William Beaumont Hosp, Dept Med, Div Prevent Med, Royal Oak, MI 48073 USA

来源：

OBESITY SURGERY | 2010年 / 20卷 / 07期

关键词：

Obesity; Vitamin D; Bariatric surgery; Metabolic bone disease; Secondary hyperparathyroidism; PARATHYROID-HORMONE; SURGERY; BONE; PREVENTION; CALCIUM; CANCERS; DISEASE; RISK;

D O I：

10.1007/s11695-010-0178-z

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Obesity as well as bariatric surgery may increase the risk for vitamin D deficiency. We retrospectively compared vitamin D levels in obese patients (n = 123) prior to bariatric surgery and 1 year postoperatively. We also evaluated parathyroid hormone levels (PTH) 1 year after surgery. A higher percentage of patients had baseline vitamin D deficiency (86%), defined as 25-hydroxy vitamin D < 32 ng/mL, compared with the 1-year (post-surgical) levels, (70%; p < 0.001). Body mass index (BMI) inversely correlated with vitamin D deficiency at baseline (r = -0.3, p = 0.06) and at the postoperative follow-up (r = -0.2, p = 0.013). One third of the postoperative population had secondary hyperparathyroidism, defined by a serum PTH level > 62 pg/mL; however, postoperative PTH and vitamin D levels were unrelated (r = -0.001, p = 0.994). Pre- and postoperative vitamin D levels were inversely correlated with BMI. Secondary hyperparathyroidism was observed in 33% of patients postoperatively; however, this did not correlate with vitamin D.

引用

页码：949 / 952

页数：4

共 20 条

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