A 65-nm CMOS Fully-Integrated Circulating Tumor Cell and Exosome Analyzer Using an On-Chip Vector Network Analyzer and a Transmission-Line-Based Detection Window

被引：0

作者：

Nakanishi, Taiki ^{[1
]}

Matsunaga, Maya ^{[1
]}

Murakami, Shunya ^{[1
]}

Kobayashi, Atsuki ^{[1
]}

Niitsu, Kiichi ^{[1
,2
]}

机构：

[1] Nagoya Univ, Nagoya, Aichi, Japan

[2] JST PRESTO, Saitama, Japan

来源：

24TH ASIA AND SOUTH PACIFIC DESIGN AUTOMATION CONFERENCE (ASP-DAC 2019) | 2019年

关键词：

circulating tumor cell (CTC); on-chip VNA; CMOS; dielectric properties; coplanar waveguide (CPW) line; BIOSENSOR;

D O I：

10.1145/3287624.3287750

中图分类号：

TP301 [理论、方法];

学科分类号：

081202 ;

摘要：

A fully-integrated CMOS circuit based on a vector network analyzer (VNA) and a transmission-line-based detection window for circulating tumor cell (CTC) and exosome analysis is presented. We have introduced a fully-integrated architecture, which eliminates the undesired parasitic components and enables high-sensitivity, for analysis of extremely low-concentration CTC in blood. To validate the operation of the proposed system, a test chip was fabricated using 65-nm CMOS technology. Measurement results shows the effectiveness of the approach.

引用

页码：19 / 20

页数：2

共 3 条

[1] A Fully-Integrated Circulating Tumor Cell Analyzer Using an On-Chip Vector Network Analyzer and a Transmission-Line-Based Detection Window in 65-nm CMOS
Nakanishi, Taiki
Matsunaga, Maya
Kobayashi, Atsuki
Nakazato, Kazuo
Niitsu, Kiichi
2017 IEEE BIOMEDICAL CIRCUITS AND SYSTEMS CONFERENCE (BIOCAS), 2017,
[2] A 65-nm CMOS Fully Integrated Analysis Platform Using an On-Chip Vector Network Analyzer and a Transmission-Line-Based Detection Window for Analyzing Circulating Tumor Cell and Exosome
Niitsu, Kiichi
Nakanishi, Taiki
Murakami, Shunya
Matsunaga, Maya
Kobayashi, Atsuki
Karim, Nissar Mohammad
Ito, Jun
Ozawa, Naoya
Hase, Tetsunari
Tanaka, Hiromasa
Sato, Mitsuo
Kondo, Hiroki
Ishikawa, Kenji
Odaka, Hidefumi
Hasegawa, Yoshinori
Hori, Masaru
Nakazato, Kazuo
IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, 2019, 13 (02) : 470 - 479
[3] A 40-GHz Fully-Integrated CMOS-Based Biosensor Circuit With an On-Chip Vector Network Analyzer for Circulating Tumor Cells Analysis
Nakanishi, Taiki
Murakami, Shunya
Kobayashi, Atsuki
Islam, Md Zahidul
Niitsu, Kiichi
2019 IEEE NORDIC CIRCUITS AND SYSTEMS CONFERENCE (NORCAS) - NORCHIP AND INTERNATIONAL SYMPOSIUM OF SYSTEM-ON-CHIP (SOC), 2019,

← 1 →