Cancer nanomedicine: is targeting our target?

被引：193

作者：

Lammers, Twan ^{[1
,2
,3
]}

Kiessling, Fabian ^{[1
]}

Ashford, Marianne ^{[4
]}

Hennink, Wim ^{[3
]}

Crommelin, Daan ^{[3
]}

Storm, Gert ^{[2
,3
]}

机构：

[1] RWTH Aachen Univ Clin, Inst Expt Mol Imaging, Dept Nanomed & Theranost, D-52074 Aachen, Germany

[2] Univ Twente, MIRA Inst Biomed Technol & Tech Med, Dept Targeted Therapeut, NL-7500 AE Enschede, Netherlands

[3] Univ Utrecht, Utrecht Inst Pharmaceut Sci, Dept Pharmaceut, NL-3584 CG Utrecht, Netherlands

[4] AstraZeneca, Pharmaceut Sci, Innovat Med, Macclesfield SK10 2NA, Cheshire, England

来源：

NATURE REVIEWS MATERIALS | 2016年 / 1卷 / 09期

基金：

欧洲研究理事会;

关键词：

DELIVERY;

D O I：

10.1038/natrevmats.2016.69

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Nanomedicine may have a delivery problem. Rigorous, realistic and holistic rethinking is needed to improve nanomedicine performance and increase patient benefit.

引用

页数：2

共 5 条

[1] Personalized Nanomedicine [J].

Lammers, Twan ;

Rizzo, Larissa Y. ;

Storm, Gert ;

Kiessling, Fabian .

CLINICAL CANCER RESEARCH, 2012, 18 (18) :4889-4894

[2] Nanomedicine gets personal [J].

Tietjen, Gregory T. ;

Saltzman, W. Mark .

SCIENCE TRANSLATIONAL MEDICINE, 2015, 7 (314)

[3] Does Nanomedicine Have a Delivery Problem? [J].

Torrice, Michael .

ACS CENTRAL SCIENCE, 2016, 2 (07) :434-437

[4] Cancer nanomedicines: So many papers and so few drugs! [J].

Venditto, Vincent J. ;

Szoka, Francis C., Jr. .

ADVANCED DRUG DELIVERY REVIEWS, 2013, 65 (01) :80-88

[5] Analysis of nanoparticle delivery to tumours [J].

Wilhelm, Stefan ;

Tavares, Anthony J. ;

Dai, Qin ;

Ohta, Seiichi ;

Audet, Julie ;

Dvorak, Harold F. ;

Chan, Warren C. W. .

NATURE REVIEWS MATERIALS, 2016, 1 (05)

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