Comparing the calcium bioavailability from two types of nano-sized enriched milk using in-vivo assay

被引:40
作者
Erfanian, Arezoo [1 ]
Rasti, Babak [1 ]
Manap, Yazid [2 ]
机构
[1] Univ Malaysia Sabah, Fac Food Sci & Nutr, Kota Kinabalu 88400, Sabah, Malaysia
[2] Univ Putra Malaysia, Halal Prod Res Inst, Serdang 43400, Malaysia
关键词
Calcium; Nano-particle; Enrichment; Prebiotic; Vitamin; POSTMENOPAUSAL WOMEN; ABSORPTION; CITRATE;
D O I
10.1016/j.foodchem.2016.07.116
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Calcium bioavailability from two types of enriched (calcium citrate and calcium carbonate) milks homogenized to a nano-sized particle distribution has been studied among 48 female Sprauge-dawley rats. Skim milk powder was enriched with some essential nutrients (Inulin, DHA & EPA, vitamins B-6, K-1, and D-3) as enhancers of calcium bioavailability according to recommended dietary allowances of the West European and North American. Ovariectomized and ovariectomized-osteoporosis rats were used as a menopause and menopause-osteoporosis model, respectively. Although, nano-sized enriched milk powders had the greatest calcium bioavailability among the groups, but bioavailability of nano-sized calcium carbonate-enriched-milk was significantly (P < 0.05) better than nano-sized calcium citrate-enriched milk. Moreover, the trends were similar for bone calcium, strength and morphology. Therefore, based on the current results the calcium carbonate nano-sized enriched milk could be an effective enriched milk powder in ovariectomized-osteoporosis and ovariectomized rats as a model of menopause osteoporosis and menopause women. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码:606 / 613
页数:8
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