A label-free electrochemical assay for quantification of gene-specific methylation in a nucleic acid sequence

被引：55

作者：

Dai, Zong ^{[1
]}

Hu, Xiao ^{[1
]}

Wu, Hai ^{[1
]}

Zou, Xiaoyong ^{[1
]}

机构：

[1] Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 12期

基金：

中国国家自然科学基金;

关键词：

DNA METHYLATION; HYBRIDIZATION; FILM;

D O I：

10.1039/c2cc15398j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A label-free electrochemical method is developed for simple and convenient quantification of gene-specific DNA hypermethylation in a DNA sequence without PCR amplification, bisulfite conversion or labeling processes.

引用

页码：1769 / 1771

页数：3

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