Lignan glycosides from Neoalsomitra integrifoliola

被引:24
作者
Su, Dongmin [1 ,2 ,3 ]
Tang, Wenzhao [1 ,2 ,4 ]
Hu, Youcai [1 ,2 ]
Liu, Yunbao [1 ,2 ]
Yu, Shishan [1 ,2 ]
Ma, Shuanggang [1 ,2 ]
Qu, Jing [1 ,2 ]
Yu, Dequan [1 ,2 ]
机构
[1] Chinese Acad Med Sci, Inst Mat Med, Minist Educ, Key Lab Bioact Subst & Resources Utilizat Chinese, Beijing 100050, Peoples R China
[2] Peking Union Med Coll, Beijing 100050, Peoples R China
[3] Qinghai Inst Drug Control, Xining 810000, Peoples R China
[4] Shandong Acad Med Sci, Inst Mat Med, Jinan 250062, Peoples R China
来源
JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 05期
关键词
D O I
10.1021/np070565+
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Five new lignan glycosides, (8R*,7'S*,8'R*)-5,5'-dimethoxy-7-oxolariciresinol 9'-O-beta-D-xylopyranoside (1), (7S,8R)-dihydrodehydrodiconiferyl alcohol 9-O-beta-D-apiofuranosyl-(1 -> 6)-O-beta-D-glucopyranoside (2), (7S*,8R*,7'S*,8R*)-4,4'-dimethoxyhuazhongilexin 9-O-beta-D-xylopyranoside (4), (7S*,8R*,7'S*,8'R*)-4,4'-dimethoxyhuazhongilexin 9-O-alpha-L-arabinopyranoside (5), and (7S*,8R*,7'S*,8'R*)-huazhongilexin 9-O-(2-feruloyl)-beta-D-xylopyranoside (6), together with four known compounds, (7R,8S)-dihydrodehydrodiconiferyl alcohol 9-O-beta-D-glucopyranoside (3), the 9-O-beta-D-xylopyranoside of icariol A(2) (7), huazhongilexin (8), and nudiposide (9), were isolated from the leaves of Neoalsomitra integrifoliola. Their structures were determined by spectroscopic analysis and chemical methods. Compounds 2, 3, 8, and 9 showed weak anti-inflammatory activities.
引用
收藏
页码:784 / 788
页数:5
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