The inhibitory effect of honokiol, a natural plant product, on vestibular schwannoma cells

被引：12
作者：
Lee, Jong Dae [2 ]
Lee, Jae Yong [2 ]
Baek, Byoung Joon [2 ]
Lee, Byung Don [2 ]
Koh, Yoon Woo [1 ]
Lee, Won-Sang [1 ]
Lee, Yu-Jin [3 ]
Kwon, Byoung-Mog [3 ]
机构：
[1] Yonsei Univ, Coll Med, Dept Otorhinolaryngol, Seoul 120752, South Korea
[2] Soonchunhyang Univ, Coll Med, Dept Otorhinolaryngol Head & Neck Surg, Puchon, South Korea
[3] Korea Res Inst Biosci & Biotechnol, Lab Chem Biol & Genom, Taejon, South Korea
来源：
LARYNGOSCOPE | 2012年 / 122卷 / 01期
基金：
新加坡国家研究基金会;
关键词：
Honokiol; vestibular schwannoma; apoptosis; ERK; Level of Evidence: 2c; REGULATED KINASE PATHWAY; IN-VIVO; GROWTH; APOPTOSIS; CANCER; ACTIVATION; ANGIOGENESIS; XENOGRAFTS; PREVENTION; INDUCTION;
D O I：
10.1002/lary.21781
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Objectives/Hypothesis: As the molecular biology of vestibular schwannoma (VS) is better understood, new means of targeting the pathways involved for intervention in schwannoma cells are being developed. Honokiol, a bioactive constituent of Magnolia officinalis, has attracted attention due to its diverse biological effects. This study was conducted to determine the inhibitory effect of honokiol on schwannoma cell proliferation.
引用
收藏
页码：162 / 166
页数：5
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