The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis

被引:8
|
作者
Alakoski, Anna [1 ,2 ]
Hervonen, Kaisa [1 ,2 ]
Mansikka, Eriika [2 ]
Reunala, Timo [1 ,2 ]
Kaukinen, Katri [2 ,3 ]
Kivela, Laura [2 ]
Laurikka, Pilvi [2 ]
Huhtala, Heini [4 ]
Kurppa, Kalle [5 ,6 ,7 ,8 ]
Salmi, Teea [1 ,2 ]
机构
[1] Tampere Univ Hosp, Dept Dermatol, Tampere 33521, Finland
[2] Tampere Univ, Fac Med & Hlth Technol, Celiac Dis Res Ctr, Tampere 33014, Finland
[3] Tampere Univ Hosp, Dept Internal Med, Tampere 33521, Finland
[4] Tampere Univ, Fac Social Sci, Tampere 33014, Finland
[5] Tampere Univ Hosp, Dept Paediat, Tampere 33521, Finland
[6] Tampere Univ, Ctr Child Hlth Res, Tampere 33521, Finland
[7] Seinajoki Cent Hosp, Dept Pediat, Seinajoki 60220, Finland
[8] Univ Consortium Seinajoki, Seinajoki 60220, Finland
基金
芬兰科学院;
关键词
dermatitis herpetiformis; coeliac disease; gluten-free diet; oats; quality of life; complications; follow-up; GLUTEN-FREE DIET; CELIAC-DISEASE; FOLLOW-UP; TRANSGLUTAMINASE ANTIBODIES; GASTROINTESTINAL SYMPTOMS; TISSUE TRANSGLUTAMINASE; VILLOUS ATROPHY; SKIN-LESIONS; PREVALENCE; ADULTS;
D O I
10.3390/nu12041060
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The treatment of choice for dermatitis herpetiformis (DH), a cutaneous manifestation of coeliac disease, is a life-long gluten-free diet (GFD). In a GFD, wheat, rye and barley should be strictly avoided, but the role of oats is more controversial. This study aimed to investigate the safety and long-term quality of life and health effects of oat consumption in 312 long-term treated DH patients. Baseline data were gathered from patient records and follow-up data from questionnaires or interviews, and validated questionnaires were used to assess quality of life. We found that altogether 256 patients (82%) were consuming oats as part of their GFD at the follow-up. Long-term follow-up data showed that there were no differences in the presence of long-term illnesses, coeliac disease complications or the usage of medication between those consuming and not consuming oats. However, oat consumers had a better quality of life and reported ongoing gastrointestinal symptoms less frequently (4% vs 19%, p = 0.004) at the follow-up than those not consuming oats. The study established that oats are safe for DH patients and in the long-term seem to improve the quality of life of DH patients.
引用
收藏
页数:10
相关论文
共 50 条
  • [31] Quality of Life and Long-Term Therapy in Patients with Chronic Myeloid Leukemia
    Flynn, Kathryn E.
    Atallah, Ehab
    CURRENT HEMATOLOGIC MALIGNANCY REPORTS, 2016, 11 (02) : 80 - 85
  • [32] Neoadjuvant Leuprolide Therapy with Radical Prostatectomy: Long-term Effects on Health-related Quality of Life
    Chen, Michael C.
    Kilday, Patrick S.
    Elliott, Peter A.
    Artenstein, Daniel
    Slezak, Jeff
    Jacobsen, Steven J.
    Chien, Gary W.
    EUROPEAN UROLOGY FOCUS, 2021, 7 (04): : 779 - 787
  • [33] Long-term outcomes and quality of life of patients with Hirschsprung disease: a systematic review and meta-analysis
    Ying Dai
    Yongfang Deng
    Yan Lin
    Runxian Ouyang
    Le Li
    BMC Gastroenterology, 20
  • [34] Fecal Incontinence Affecting Quality of Life and Social Functioning Among Long-Term Gynecological Cancer Survivors
    Dunberger, Gail
    Lind, Helena
    Steineck, Gunnar
    Waldenstrom, Ann-Charlotte
    Nyberg, Tommy
    al-Abany, Massoud
    Nyberg, Ullakarin
    Avall-Lundqvist, Elisabeth
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2010, 20 (03) : 449 - 460
  • [35] Long-term effects on the quality of life following cochlear implant treatment in older patients
    Issing, Christian
    Holtz, Svea
    Loth, Andreas G.
    Baumann, Uwe
    Pantel, Johannes
    Stover, Timo
    EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2022, 279 (11) : 5135 - 5144
  • [36] Immediate outcome, long-term function and quality of life after extended colectomy with ileorectal or ileosigmoid anastomosis
    Duclos, J.
    Lefevre, J. H.
    Lefrancois, M.
    Lupinacci, R.
    Shields, C.
    Chafai, N.
    Tiret, E.
    Parc, Y.
    COLORECTAL DISEASE, 2014, 16 (08) : O288 - O296
  • [37] Long-term impact of stroke on patients' health-related quality of life
    De Wit, Liesbet
    Theuns, Peter
    Dejaeger, Eddy
    Devos, Stefanie
    Gantenbein, Andreas R.
    Kerckhofs, Eric
    Schuback, Birgit
    Schupp, Wilfried
    Putman, Koen
    DISABILITY AND REHABILITATION, 2017, 39 (14) : 1435 - 1440
  • [38] Comparison of Long-term Quality-of-Life Outcomes in Vestibular Schwannoma Patients
    Robinett, Zachary N.
    Walz, Patrick C.
    Miles-Markley, Beth
    Moberly, Aaron C.
    Welling, D. Bradley
    OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2014, 150 (06) : 1024 - 1032
  • [39] Long-term medical and quality of life outcomes among voluntary liver donors
    Bhatti, Abu Bakar Hafeez
    Naqvi, Wajih
    Mohsan, Maheen
    Iqbal, Moeza
    Arshad, Eman Binte
    Khan, Zainab
    Waheed, Anum
    Zia, Haseeb Haider
    Khan, Nusrat Yar
    Yousafzai, Abdul Wahab
    Khan, Nasir Ayub
    JOURNAL OF GASTROINTESTINAL SURGERY, 2024, 28 (05) : 731 - 737
  • [40] Long-term outcome and quality of life in patients with total colonic aganglionosis in the Netherlands
    Roorda, D.
    Witvliet, M. J.
    Wellens, L. M.
    Schulten, D. V.
    Sloots, C. E. J.
    de Blaauw, I.
    Broens, P. M. A.
    Oosterlaan, J.
    van Heurn, L. W. E.
    van der Steeg, A. F. W.
    COLORECTAL DISEASE, 2018, 20 (08) : 719 - 726