Endocrine disruption in sexual differentiation and puberty - What do pseudohermaphroditic polar bears have to do with the practice of pediatrics?

被引：19
作者：
Gulledge, CC
Burow, ME
McLachlan, JA
机构：
[1] Tulane Univ, Ctr Bioenvironm Res, New Orleans, LA 70112 USA
[2] Xavier Univ, Ctr Bioenvironm Res, New Orleans, LA 70125 USA
[3] Tulane Univ, Dept Ecol & Evolut Biol, New Orleans, LA 70118 USA
[4] Tulane Univ, Dept Pharmacol, New Orleans, LA 70118 USA
来源：
PEDIATRIC CLINICS OF NORTH AMERICA | 2001年 / 48卷 / 05期
关键词：
D O I：
10.1016/S0031-3955(05)70371-0
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
What do pseudohermaphroditic polar bears and girls with premature breast development have in common? Hormones. Sexual differentiation and the initiation of secondary sexual characteristics, such as breast growth, are both under the control of the sex hormones estrogen and androgen. Abnormal differentiation of the internal or external genitalia in bears and early onset of breast development in girls also may have a con-anon element-exposure to environmental hormones.
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页码：1223 / +
页数：19
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