Atherosclerosis and complement: anaphylatoxin C5a as a new risk marker and therapeutic target

被引：2
|
作者：
Speidl, Walter S. [1 ]
机构：
[1] Med Univ Vienna, Dept Internal Med 2, A-1090 Vienna, Austria
来源：
CLINICAL LIPIDOLOGY | 2011年 / 6卷 / 02期
关键词：
anaphylatoxin; atherosclerosis; C5a; complement; inflammation; plaque; RECEPTOR-DEFICIENT MICE; PERCUTANEOUS CORONARY INTERVENTION; PLASMINOGEN-ACTIVATOR INHIBITOR-1; ACUTE MYOCARDIAL-INFARCTION; C-REACTIVE PROTEIN; COMPONENT C5A; HUMAN MACROPHAGES; ENDOTHELIAL-CELLS; MAST-CELLS; EXPRESSION;
D O I：
10.2217/CLP.11.6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：123 / 126
页数：4
相关论文
共 50 条
  • [1] Inactivation of the complement anaphylatoxin C5a by secreted products of parasitic nematodes
    Rees-Roberts, Dominic
    Mullen, Lisa M.
    Gounaris, Kleoniki
    Selkirk, Murray E.
    INTERNATIONAL JOURNAL FOR PARASITOLOGY, 2010, 40 (05) : 527 - 532
  • [2] Complement-derived anaphylatoxin C5a protects against glutamate-mediated neurotoxicity
    Osaka, H
    Mukherjee, P
    Aisen, PS
    Pasinetti, GM
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1999, 73 (03) : 303 - 311
  • [3] The role of complement anaphylatoxin C5a in neurodegeneration: implications in Alzheimer's disease
    Mukherjee, P
    Pasinetti, GM
    JOURNAL OF NEUROIMMUNOLOGY, 2000, 105 (02) : 124 - 130
  • [4] Molecular analysis of the bovine anaphylatoxin C5a receptor
    Nemali, Sailasree
    Siemsen, Daniel W.
    Nelson, Laura K.
    Bunger, Peggy L.
    Faulkner, Craig L.
    Rainard, Pascal
    Gauss, Katherine A.
    Jutila, Mark A.
    Quinn, Mark T.
    JOURNAL OF LEUKOCYTE BIOLOGY, 2008, 84 (02) : 537 - 549
  • [5] Complement anaphylatoxin C3a and C5a formation in premature children with respiratory distress
    Enskog, A
    Bengtsson, A
    Bengtson, JP
    Heideman, M
    Andreasson, S
    Larsson, L
    EUROPEAN JOURNAL OF PEDIATRICS, 1996, 155 (01) : 41 - 45
  • [6] Regulators of the anaphylatoxin C5a
    Taylor, SM
    Fairlie, DP
    EXPERT OPINION ON THERAPEUTIC PATENTS, 2000, 10 (04) : 449 - 458
  • [7] Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis
    Kourtzelis, Ioannis
    Markiewski, Maciej M.
    Doumas, Michael
    Rafail, Stavros
    Kambas, Konstantinos
    Mitroulis, Ioannis
    Panagoutsos, Stelios
    Passadakis, Ploumis
    Vargemezis, Vasilios
    Magotti, Paola
    Qu, Hongchang
    Mollnes, Tom Eirik
    Ritis, Konstantinos
    Lambris, John D.
    BLOOD, 2010, 116 (04) : 631 - 639
  • [8] Complement Regulation in Human Tenocytes under the Influence of Anaphylatoxin C5a
    Silawal, Sandeep
    Kohl, Benjamin
    Shi, Jingjian
    Schulze-Tanzil, Gundula
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (06) : 1 - 13
  • [9] Complement anaphylatoxin C3a as a novel independent prognostic marker in heart failure
    Gombos, Timea
    Forhecz, Zsolt
    Pozsonyi, Zoltan
    Szeplaki, Gabor
    Kunde, Jan
    Fust, George
    Janoskuti, Livia
    Karadi, Istvan
    Prohaszka, Zoltan
    CLINICAL RESEARCH IN CARDIOLOGY, 2012, 101 (08) : 607 - 615
  • [10] Anaphylatoxin receptor promiscuity for commonly used complement C5a peptide agonists
    Li, Xaria X.
    Clark, Richard J.
    Woodruff, Trent M.
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 100
12345