Scale-up of erythritol production by an osmophilic mutant of Candida magnoliae

被引:63
作者
Koh, ES
Lee, TH
Lee, DY
Kim, HJ
Ryu, YW
Seo, JH [1 ]
机构
[1] Seoul Natl Univ, Dept Agr Biotechnol, Seoul 151742, South Korea
[2] Seoul Natl Univ, New Biomat Agr Res Ctr, Seoul 151742, South Korea
[3] Ajou Univ, Dept Mol Sci & Technol, Suwon 442749, South Korea
关键词
Candida magnoliae; erythritol; fed-batch fermentation; scale-up;
D O I
10.1023/B:BILE.0000007076.64338.ce
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Erythritol production by an osmophilic mutant of Candida magnoliae was performed in fermentations of up 50 l to develop an optimized commercial process. By simultaneous feeding glucose and yeast extract, erythritol productivity of 1.2 g l(-1) h(-1) was reached giving 200 g erythritol l(-1) with a yield of 0.43 g g(-1).
引用
收藏
页码:2103 / 2105
页数:3
相关论文
共 50 条
[21]   Distributed production: Scale-up vs experience [J].
Patience G.S. ;
Boffito D.C. .
Journal of Advanced Manufacturing and Processing, 2020, 2 (02)
[22]   Scale-up and kinetic modeling for bioethanol production [J].
Imamoglu, Esra ;
Sukan, Fazilet Vardar .
BIORESOURCE TECHNOLOGY, 2013, 144 :311-320
[23]   Actinomycetes Scale-Up for the Production of the Antibacterial, Nocathiacin [J].
Junker, Beth ;
Walker, Andre ;
Hesse, Michelle ;
Lester, Mike ;
Christensen, Jens ;
Connors, Neal .
BIOTECHNOLOGY PROGRESS, 2009, 25 (01) :176-188
[24]   Screening and production of erythritol by newly isolated osmophilic yeast-like fungi [J].
Lin, SJ ;
Wen, CY ;
Liau, JC ;
Chu, WS .
PROCESS BIOCHEMISTRY, 2001, 36 (12) :1249-1258
[25]   Fermentative Production of Monorhamnolipids in Pilot Scale - Challenges in Scale-Up [J].
Kuepper, Benjamin ;
Mause, Anika ;
Halka, Lisa ;
Imhoff, Adam ;
Nowacki, Christian ;
Wichmann, Rolf .
CHEMIE INGENIEUR TECHNIK, 2013, 85 (06) :834-840
[26]   Scale-up of dextransucrase production by Leuconostoc mesenteroides in fed batch fermentation [J].
Michelena, GL ;
Martínez, A ;
Bell, A ;
Carrera, E ;
Valencia, R .
BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY, 2003, 46 (03) :455-459
[27]   Scale-Up of Academic Mesenchymal Stromal Cell Production [J].
Laroye, Caroline ;
Gauthier, Melanie ;
Morello, Jessica ;
Charif, Naceur ;
Cannard, Veronique Latger ;
Bonnet, Celine ;
Lozniewski, Alain ;
Tchirkov, Andrei ;
De Isla, Natalia ;
Decot, Veronique ;
Reppel, Loic ;
Bensoussan, Daniele .
JOURNAL OF CLINICAL MEDICINE, 2023, 12 (13)
[28]   Prelude to rational scale-up of penicillin production: a scale-down study [J].
Guan Wang ;
Ju Chu ;
Henk Noorman ;
Jianye Xia ;
Wenjun Tang ;
Yingping Zhuang ;
Siliang Zhang .
Applied Microbiology and Biotechnology, 2014, 98 :2359-2369
[29]   Prelude to rational scale-up of penicillin production: a scale-down study [J].
Wang, Guan ;
Chu, Ju ;
Noorman, Henk ;
Xia, Jianye ;
Tang, Wenjun ;
Zhuang, Yingping ;
Zhang, Siliang .
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2014, 98 (06) :2359-2369
[30]   Process Development and Scale-up Comparisons for Transient Production of AAV [J].
Stadelman, Robert ;
Gillmeister, Michael ;
Startt, Don .
MOLECULAR THERAPY, 2020, 28 (04) :543-543