A miniature multichannel preamplifier for recording electrophysiological activity in freely moving animals

A design of a miniature lightweight multichannel preamplifier for recording electrophysiological activity in freely moving small animals is presented. The advantages of this construction include the possibility to obtain differential multichannel recording of neuronal activity, EEG and evoked potentials, relatively simple fabrication and exploitation. If necessary, the preamplifier may be easily disassembled for repair. Fine and flexible cable and "soft" hanger do not disturb free movement of an animal. The lightweight construction may be used for recording neuronal activity even in mice performing spatial task in Morris water maze.