Copper(I) Iodide Catalyzed Cross-Coupling Reaction of Terminal Alkynes with 1-Bromoalkynes: A Simple Synthesis of Unsymmetrical Buta-1,3-diynes

被引：49

作者：

Wang, Shihua ^{[1
]}

Yu, Lin ^{[1
]}

Li, Pinhua ^{[1
]}

Meng, Lingguo ^{[1
]}

Wang, Lei ^{[1
,2
]}

机构：

[1] Huaibei Normal Univ, Dept Chem, Huaibei 235000, Anhui, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2011年 / 10期

基金：

中国国家自然科学基金;

关键词：

alkynes; catalysis; cross-coupling; alkadiynes; HOMOCOUPLING REACTION; EFFICIENT SYNTHESIS; SELECTIVE SYNTHESIS; ROOM-TEMPERATURE; ROUTE; PANAXYTRIOL; POLYMERS; DIYNES;

D O I：

10.1055/s-0030-1259998

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple synthesis of unsymmetrical buta-1,3-diynes by cross-coupling of terminal alkynes with 1-bromoalkynes in the presence of copper(I) iodide and tris(o-tolyl) phosphine was developed that gives good yields under simple and mild reaction conditions. The scope and limitations of the cross-coupling reaction were investigated.

引用

页码：1541 / 1546

页数：6

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