Synthesis of Some Substituted Phenylthiazolyl 1,3,5-Triazine Derivatives

被引:0
作者
Gahtori, P. [1 ]
Singh, A. [1 ]
Ghosh, S. K. [2 ]
Das, A. [2 ]
Archana, U. [3 ]
机构
[1] Devsthali Vidyapeeth Coll Pharm, Lalpur 263148, Rudrapur, India
[2] Dibrugarh Univ, Dept Pharmaceut Sci, Dibrugarh 786004, Assam, India
[3] Shri Guru Ram Rai Inst Technol & Sci, Dehra Dun 248001, Uttar Pradesh, India
关键词
Synthesis; Phenylthiazolyl; 1,3,5-Triazine derivatives;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of some substituted phenylthiazolyl 1,3,5-triazine derivatives 4b-12b were obtained by two steps substitution reaction of cyanotic chloride with various nucleophilic amines like diisopropylamine, morpholine, diphenyl amine in presence of aqueous media and subsequently with, synthesized substituted phenylthiazolyl-2-amines. Molecular structures of the synthesized compounds were confirmed by FTIR, (1)H NMR, (13)C NMR and elemental analyses.
引用
收藏
页码:1189 / 1192
页数:4
相关论文
共 50 条
  • [21] Synthesis and antitumor activity of novel 2-amino-4-(3,5,5-trimethyl-2-pyrazolino)-1,3,5-triazine derivatives
    Brzozowski, Z
    Saczewski, F
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2002, 37 (09) : 709 - 720
  • [22] Synthesis and Biological Evaluation of Novel 6-Hydrazinyl-2,4-bismorpholino pyrimidine and 1,3,5-Triazine Derivatives as Potential Antitumor Agents
    Zhu, Wufu
    Liu, Yajing
    Zhao, Yanfang
    Wang, Haiyan
    Tan, Li
    Fan, Weijie
    Gong, Ping
    ARCHIV DER PHARMAZIE, 2012, 345 (10) : 812 - 821
  • [23] Design and Development of Novel 1,3,5-Triazine Acetamides as Local Anaesthetics Agents
    Li, Pei-Xing
    Zhao, Qin-Ling
    Wang, Shi-Lei
    Lu, Yan-Min
    LATIN AMERICAN JOURNAL OF PHARMACY, 2016, 35 (03): : 529 - 536
  • [24] Synthesis and Surface/Interfacial Properties of Novel Dialkyl Disulfonate Gemini Surfactants Derived from 1,3,5-triazine
    Niu, Ruixia
    Wang, Chao
    Song, Hua
    Wang, Jingling
    Wang, Daqiang
    Ren, Weidong
    TENSIDE SURFACTANTS DETERGENTS, 2016, 53 (06) : 595 - 600
  • [25] Pseudo porphyrinyl amino acids based on 1,3,5-triazine scaffold: new tools for the synthesis of peptidic porphyrins
    Chaleix, Vincent
    Sol, Vincent
    Krausz, Pierre
    TETRAHEDRON LETTERS, 2011, 52 (23) : 2977 - 2979
  • [26] In silico ADMET study, docking, synthesis and antimalarial evaluation of thiazole-1,3,5-triazine derivatives as Pf-DHFR inhibitor
    Supriya Sahu
    Surajit Kumar Ghosh
    Prashant Gahtori
    Udaya Pratap Singh
    Dibya Ranjan Bhattacharyya
    Hans Raj Bhat
    Pharmacological Reports, 2019, 71 : 762 - 767
  • [27] In silico ADMET study, docking, synthesis and antimalarial evaluation of thiazole-1,3,5-triazine derivatives as Pf-DHFR inhibitor
    Sahu, Supriya
    Ghosh, Surajit Kumar
    Gahtori, Prashant
    Singh, Udaya Pratap
    Bhattacharyya, Dibya Ranjan
    Bhat, Hans Raj
    PHARMACOLOGICAL REPORTS, 2019, 71 (05) : 762 - 767
  • [28] Synthesis of glycosides in which the aglycon is an N-(hydroxymethyl)amino-1,3,5-triazine derivative
    Bagga, K
    Dua, G
    Williams, G
    Simmonds, RJ
    GLYCOCONJUGATE JOURNAL, 1997, 14 (04) : 519 - 521
  • [29] Synthesis of glycosides in which the aglycon is an N-(Hydroxymethyl)amino-1,3,5-triazine derivative
    Kishore Bagga
    Geeta Dua
    Gerallt Williams
    Richard J Simmonds
    Glycoconjugate Journal, 1997, 14 : 519 - 521
  • [30] Rigid trisporphyrin with 1,3,5-triazine core: Synthesis, spectroscopy, and DABCO-induced self-assembly properties
    Huang, Chunhua
    Shen, Bin
    Wang, Kang
    Lu, Jing'an
    Sun, Xiao'fei
    JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, 2020, 24 (08) : 1066 - 1073