The DASH Diet and Insulin Sensitivity

被引:58
作者
Hinderliter, Alan L. [1 ]
Babyak, Michael A. [2 ]
Sherwood, Andrew [2 ]
Blumenthal, James A. [2 ]
机构
[1] Univ N Carolina, Dept Med, Div Cardiol, Chapel Hill, NC 27599 USA
[2] Duke Univ, Med Ctr, Dept Psychiat & Behav Sci, Durham, NC 27710 USA
基金
美国国家卫生研究院;
关键词
Hypertension; Blood pressure; Diabetes; Insulin sensitivity; DASH diet; Exercise; Physical activity; Weight loss; Lifestyle modification; IMPAIRED GLUCOSE-TOLERANCE; PRESSURE-LOWERING DRUGS; LIFE-STYLE INTERVENTION; CORONARY-HEART-DISEASE; BLOOD-PRESSURE; DIABETES-MELLITUS; WEIGHT-LOSS; RISK-FACTORS; EXERCISE; HYPERTENSION;
D O I
10.1007/s11906-010-0168-5
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Lifestyle modifications, including adoption of the Dietary Approaches to Stop Hypertension (DASH) dietary pattern, weight loss in individuals who are overweight or obese, and physical activity, are effective in the prevention and treatment of hypertension. A healthy lifestyle may also have beneficial effects on metabolic abnormalities, such as insulin resistance, that are associated with high blood pressure. This review examines the independent and combined effects of the DASH diet and weight loss plus exercise on blood pressure and insulin sensitivity, with a focus on recently published results from the ENCORE study. Our data suggest that the DASH eating plan alone lowers blood pressure in overweight individuals with higher than optimal blood pressure, but significant improvements in insulin sensitivity are observed only when the DASH diet is implemented as part of a more comprehensive lifestyle modification program that includes exercise and weight loss.
引用
收藏
页码:67 / 73
页数:7
相关论文
共 50 条
[1]   Diabetes in treated hypertension is common and carries a high cardiovascular risk: results from a 28-year follow-up [J].
Almgren, Torbjorn ;
Wilhelmsen, Lars ;
Samuelsson, Ola ;
Himmelmann, Anders ;
Rosengren, Annika ;
Andersson, Ove K. .
JOURNAL OF HYPERTENSION, 2007, 25 (06) :1311-1317
[2]  
[Anonymous], CARDIOVASCULAR DIS E
[3]  
Appel LJ, 2003, JAMA-J AM MED ASSOC, V289, P2083, DOI 10.1001/jama.289.16.2083
[4]   A clinical trial of the effects of dietary patterns on blood pressure [J].
Appel, LJ ;
Moore, TJ ;
Obarzanek, E ;
Vollmer, WM ;
Svetkey, LP ;
Sacks, FM ;
Bray, GA ;
Vogt, TM ;
Cutler, JA ;
Windhauser, MM ;
Lin, PH ;
Karanja, N .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 336 (16) :1117-1124
[5]   The effect of the PREMIER interventions on insulin sensitivity [J].
Ard, JD ;
Grambow, SC ;
Liu, D ;
Slentz, CA ;
Kraus, WE ;
Svetkey, LP .
DIABETES CARE, 2004, 27 (02) :340-347
[6]   Exercise and weight loss reduce blood pressure in men and women with mild hypertension - Effects on cardiovascular, metabolic, and hemodynamic functioning [J].
Blumenthal, JA ;
Sherwood, A ;
Gullette, ECD ;
Babyak, M ;
Waugh, R ;
Georgiades, A ;
Craighead, LW ;
Tweedy, D ;
Feinglos, M ;
Appelbaum, M ;
Hayano, J ;
Hinderliter, A .
ARCHIVES OF INTERNAL MEDICINE, 2000, 160 (13) :1947-1958
[7]   Effects of the Dietary Approaches to Stop Hypertension Diet Alone and in Combination With Exercise and Caloric Restriction on Insulin Sensitivity and Lipids [J].
Blumenthal, James A. ;
Babyak, Michael A. ;
Sherwood, Andrew ;
Craighead, Linda ;
Lin, Pao-Hwa ;
Johnson, Julie ;
Watkins, Lana L. ;
Wang, Jenny T. ;
Kuhn, Cynthia ;
Feinglos, Mark ;
Hinderliter, Alan .
HYPERTENSION, 2010, 55 (05) :1199-1205
[8]   Effects of the DASH Diet Alone and in Combination With Exercise and Weight Loss on Blood Pressure and Cardiovascular Biomarkers in Men and Women With High Blood Pressure The ENCORE Study [J].
Blumenthal, James A. ;
Babyak, Michael A. ;
Hinderliter, Alan ;
Watkins, Lana L. ;
Craighead, Linda ;
Lin, Pao-Hwa ;
Caccia, Carla ;
Johnson, Julie ;
Waugh, Robert ;
Sherwood, Andrew .
ARCHIVES OF INTERNAL MEDICINE, 2010, 170 (02) :126-135
[9]   ACUTE REVERSAL OF THE ENHANCED INSULIN ACTION IN TRAINED ATHLETES - ASSOCIATION WITH INSULIN-RECEPTOR CHANGES [J].
BURSTEIN, R ;
POLYCHRONAKOS, C ;
TOEWS, CJ ;
MACDOUGALL, JD ;
GUYDA, HJ ;
POSNER, BI .
DIABETES, 1985, 34 (08) :756-760
[10]   Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure [J].
Chobanian, AV ;
Bakris, GL ;
Black, HR ;
Cushman, WC ;
Green, LA ;
Izzo, JL ;
Jones, DW ;
Materson, BJ ;
Oparil, S ;
Wright, JT ;
Roccella, EJ .
HYPERTENSION, 2003, 42 (06) :1206-1252